Evidence map›Paper›PMID 40480672›Full record

ArticleBMJ open2025

Global burden attributed to alcohol and drug use among adolescents and young adults, 1990-2019: results from the Global Burden of Disease Study 2019.

Jun Li, Xiang Li, Yi Shen, Xiaolun Yang, Tang Liu

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jun LiThe Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Xiang LiDepartment of Obstetrics and Gynecology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Yi ShenThe Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Xiaolun YangDepartment of Stomatology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China yangxiaolunyy@csu.edu.cn.
Tang LiuThe Second Xiangya Hospital of Central South University, Changsha, Hunan, China.ORCID http://orcid.org/0000-0002-0040-4270

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAdolescence is a critical period characterised by significant biological growth and transformative changes in social relationships. No authoritative study has provided a comprehensive analysis of the global burden attributed to alcohol and drug use among adolescents and young adults. STUDY DESIGN, PARTICIPANTS AND

methodsData on alcohol and drug use among people aged 10-24 years were extracted from the Global Burden of Disease Study 2019. We reported the trends of death and disability-adjusted life years (DALYs) at the global, regional and national levels. We explored the sex and sociodemographic index distribution of disease burden. PRIMARY OUTCOME MEASURES: DALYs and deaths.

resultsIn 2019, the number of deaths attributed to alcohol use and drug use among people aged 10-24 years was 59 855 and 16 391, respectively. The numbers of DALYs attributed to alcohol use and drug use were 5.9 million and 4.1 million, respectively. From 1990-2019, the global DALYs rate caused by alcohol use exhibited a downward trend for both males and females. The DALYs rate attributed to drug use in females among people aged 10-24 years exhibited a downward trend, while the DALYs rate attributed to drug use in males among people aged 10-24 years exhibited an upward trend. Furthermore, the burden attributed to alcohol use and drug use was significantly higher in males than in females. Eastern Europe had the highest burden attributed to alcohol use, and High-income North America had the highest burden of drug use.

conclusionsAlcohol and drug use remain an important risk factor that poses substantial challenges to adolescent health, particularly among males. Countries must develop effective health policies and implement targeted regulatory measures.

Indexed as

Alcohol DrinkingGlobal Burden of DiseaseSubstance-Related DisordersAdolescentChildDisability-Adjusted Life YearsFemaleGlobal HealthHumansMaleQuality-Adjusted Life YearsYoung AdultAdolescentChild & adolescent psychiatryEPIDEMIOLOGYEthanolPUBLIC HEALTHSubstance misuse

Identifiers

PMID40480672
PMCPMC12161321

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.