Evidence map›Paper›PMID 40481909›Full record

ReviewAdvances in therapy2025

An Overview of Currently Available Injectable Therapies in Diabetes: A Guide to Practitioners.

Jothydev Kesavadev, Anjana Basanth, Arun Shankar, Banshi Saboo, Anjana Ranjit Mohan, Shashank Joshi, Sujoy Ghosh, Gopika Krishnan, Krishnadev Jothydev, Asha Ashik

Abstract readReview
In one paragraph

Review in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jothydev KesavadevJothydev's Diabetes and Research Centre, Trivandrum, Kerala, India. jothydev@gmail.com.ORCID http://orcid.org/0000-0001-6522-6391
Anjana BasanthJothydev's Diabetes and Research Centre, Trivandrum, Kerala, India.
Arun ShankarJothydev's Diabetes and Research Centre, Trivandrum, Kerala, India.
Banshi SabooDia Care-Diabetes Care and Hormone Clinic, Diabetology, Ahmedabad, Gujarat, India.
Anjana Ranjit MohanMadras Diabetes Research Foundation and Dr. Mohan's Diabetes Specialties Centre, Chennai, India.
Shashank JoshiJoshi Clinic, Lilavati and Sir HN RF Hospitals, Mumbai, Maharashtra, India.
Sujoy GhoshInstitute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
Gopika KrishnanJothydev's Diabetes and Research Centre, Trivandrum, Kerala, India.
Krishnadev JothydevJothydev's Diabetes and Research Centre, Trivandrum, Kerala, India.
Asha AshikDia Care-Diabetes Care and Hormone Clinic, Diabetology, Ahmedabad, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of diabetes has seen significant advancements with the introduction of various injectable therapies. Being a common chronic disorder, it is managed by doctors across all specialties worldwide. Despite the availability of new medications, healthcare professionals continue to face ambiguity due to differing terminologies and variations in regional practices. This review aims to elucidate the current therapeutic spectrum of injectable therapies in diabetes care, providing clarity on the types, mechanisms, and clinical implications of both insulin and non-insulin injections. An extensive review of existing literature was conducted, focusing on insulin injections (including short-acting, rapid-acting, ultra-rapid acting, intermediate-acting, long acting and ultra-long-acting types), non-insulin injections (such as glucagon-like peptide-1 [GLP-1] receptor agonists, dual GLP-1 and gastric inhibitory polypeptide [GIP] agonist, and amylin analogs) and co-formulations (long-acting insulin with GLP-1 or long-acting insulin with rapid acting insulin). We have included innovators and biosimilars in this review article for better understanding. Insulin therapies offer tailored glycemic control, while non-insulin injectables provide additional benefits in weight management and reduced hypoglycemia risk. This review serves as a comprehensive guide for healthcare providers worldwide to navigate the landscape of injectable treatment options in diabetes, with a focus on optimizing therapeutic outcomes through informed decision-making.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2Hypoglycemic AgentsInsulinGlucagon-Like Peptide 1Glucagon-Like Peptide-1 Receptor AgonistsHumansInjectionsGlucagon-Like Peptide 1Glucagon-Like Peptide-1 Receptor AgonistsHypoglycemic AgentsInsulinAmylin analogsClinical practiceCo-formulationsDiabetes managementGLP-1 receptor agonistsInjectable therapiesInsulinInsulin analogsNon-insulin injections

Identifiers

PMID40481909
PMCPMC12313841

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.