Evidence map›Paper›PMID 40484232›Full record

ArticleThe American journal of clinical nutrition2025

Paving the way for improved action: how nuclear techniques can advance the assessment of malnutrition.

Shruti P Shertukde, Ramya Padmanabha, Stephanie T Chung, Claire Gaudichon, Kerry S Jones, Paul Kelly, Nancy F Krebs, Anura Kurpad, Yvonne Lamers, Veronica Lopez-Teros and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Shruti P ShertukdeNutrition and Health-Related Environmental Studies Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria.
Ramya PadmanabhaNutrition and Health-Related Environmental Studies Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria; Division of Nutrition, St. John's Research Institute, Bengaluru, India.
Stephanie T ChungNational Institutes of Health, National Institute of Diabetes and Digestive Kidney Disease, Section of Paediatric Diabetes, Obesity and Metabolism Diabetes, Bethesda, MD, United States.
Claire GaudichonPhysiologie de la Nutrition et du Comportement Alimentaire, AgroParisTech, Paris, France.
Kerry S JonesNutritional Biomarker Laboratory, MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Paul KellyTropical Gastroenterology and Nutrition Group, Lusaka, Zambia; Blizard Institute, Queen Mary University of London, United Kingdom.
Nancy F KrebsSection of Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, United States.
Anura KurpadDepartment of Physiology, St. John's Medical College, Bengaluru, India.
Yvonne LamersFood, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC, Canada.
Veronica Lopez-TerosNutrition and Health-Related Environmental Studies Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria; Nutritional Laboratory, Universidad de Sonora, Sonora, Mexico.
Alida Melse-BoonstraDivision of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands.
Fatima C PereiraSchool of Biological Sciences, University of Southampton, Southampton, United Kingdom.
Carla M PradoHuman Nutrition Research Unit, Department of Agricultural, Food, and Nutritional Sciences, University of Alberta, Edmonton, AB, Canada.
Susan B RobertsGeisel School of Medicine, Dartmouth College, Hanover, NH, United States.
John ShepherdPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, Honolulu, HI, United States.
Pattanee WinichagoonInstitute of Nutrition, Mahidol University, Salaya, Nakhon Pathom, Thailand.
Jonathan C K WellsChildhood Nutrition Research Centre, Population, Policy and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Cornelia U LoechlNutrition and Health-Related Environmental Studies Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austria. Electronic address: c.u.loechl@iaea.org.
Daniel J HoffmanDepartment of Nutritional Sciences, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ, United States. Electronic address: dhoffman@sebs.rutgers.edu.

Funding

Intramural NIH HHS Z99 DK999999
6 · The paper itself

Abstract

Malnutrition in all its forms-including undernutrition, micronutrient deficiencies, and overnutrition-continues to rise globally, driven by complex structural and biological factors that contribute to an increased risk of noncommunicable diseases (NCDs). Addressing this multifaceted challenge requires precise assessment tools. To advance this effort, the International Atomic Energy Agency held a technical meeting of global experts to explore how nuclear techniques, specifically stable isotope tracers and imaging methods, and emerging technologies can enhance nutrition assessments to better address malnutrition. On the basis of the meeting's discussions, this report highlights the application of nuclear techniques to improve the measurement of body composition across life stages and disease states, assess nutrient bioavailability more holistically, elucidate nutrient flux under conditions of malnutrition, trace metabolic processes linked to NCDs, and refine nutrient requirements to better reflect diverse populations. The integration of nuclear techniques with emerging tools such as artificial intelligence and model-based compartmental analysis was emphasized as a key strategy to enhance their utility. This report also highlights the important role of nuclear techniques in addressing malnutrition and calls for interdisciplinary collaboration and reduced research silos to fully leverage these techniques to combat this condition more effectively.

Indexed as

MalnutritionNutrition AssessmentBody CompositionHumansNutritional Statusartificial intelligencebody compositionbreaking research silosdouble burden of malnutritionmodel-based compartmental analysisnutrient bioavailabilitynutrient fluxnutrient requirementsstable isotope techniques

Identifiers

PMID40484232
PMCPMC12338997

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.