Evidence map›Paper›PMID 40484722›Full record

ArticleDrug and alcohol review2025

Relationships Between Motives for Cannabis and Cannabidiol Use in People Who Co-Use: Results From the European Web Survey on Drugs.

Davide Fortin, Vincent Leroy, Patrizia Carrieri, João Matias, Tangui Barré

Abstract read
In one paragraph

Article in Drug and alcohol review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Davide FortinAix Marseille Univ, Inserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'information Médicale, ISSPAM, Marseille, France.
Vincent LeroyAix Marseille Univ, Inserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'information Médicale, ISSPAM, Marseille, France.
Patrizia CarrieriAix Marseille Univ, Inserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'information Médicale, ISSPAM, Marseille, France.
João MatiasEuropean Union Drugs Agency, Lisbon, Portugal.
Tangui BarréAix Marseille Univ, Inserm, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'information Médicale, ISSPAM, Marseille, France.ORCID 0000-0002-3439-8868

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCannabis is one of the most commonly used psychoactive substances globally. Cannabidiol (CBD) is a non-intoxicating cannabis compound increasingly used for various purposes, especially among cannabis users. However, to date, there are no data on the relationships between cannabis and CBD motives. Understanding these relationships and characterising people who co-use cannabis and CBD by their motives can help adapt marketing policies and foster CBD-based harm reduction practices for people who use cannabis.

methodsWe selected cannabis users from the third wave of the European Web Survey on Drugs conducted in 21 EU and 9 non-EU countries. Using a multilevel mixed-effects logistic regression model, we identified factors associated with CBD co-use. We computed Bonferroni-adjusted tetrachoric correlations between cannabis and CBD self-reported motives for use. We computed Spearman's correlations between the number of declared cannabis and CBD motives. We performed an ascending hierarchical classification to identify cannabis-CBD co-user profiles based on their cannabis and CBD motives.

resultsThe study sample comprised 35,789 participants (42.3% who co-used CBD). CBD use was associated with reporting cannabis therapeutic-oriented motives. The numbers of motives for cannabis and CBD use were correlated (ρ = 0.49, p < 0.001). Similar motives were highly correlated between substances. Cluster analysis revealed four different co-user profiles. DISCUSSION AND

conclusionsIndividuals who use both cannabis and CBD tend to do so for similar reasons. Considering the safe profile of CBD, further research should explore the potential harm-reduction role of partially substituting tetrahydrocannabinol-based products with CBD-based products among people who use cannabis.

Indexed as

CannabidiolMarijuana UseMotivationAdolescentAdultCannabisEuropeFemaleHumansInternetMaleMiddle AgedSurveys and QuestionnairesYoung AdultCannabidiolcannabidiolcannabisEuropemotivessurvey

Identifiers

PMID40484722
PMCPMC12405827

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.