Evidence map›Paper›PMID 40485991›Full record

ArticleAsia-Pacific journal of oncology nursing2025

Symptoms experience during the oral intake rehabilitation period following esophagectomy: A network analysis.

Hanxue Liu, Xiaoju Zhang, Jiajia Qiu, Zhenqi Lu, Chong Chen

Abstract read
In one paragraph

Article in Asia-Pacific journal of oncology nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Clinical predictors of early reflux and symptom severity after esophagectomy: a risk prediction tool.Esophagus : official journal of the Japan Esophageal Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hanxue LiuDepartment of Nursing, Fudan University Shanghai Cancer Center, Shanghai, China.
Xiaoju ZhangDepartment of Nursing, Fudan University Shanghai Cancer Center, Shanghai, China.
Jiajia QiuDepartment of Nursing, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhenqi LuDepartment of Nursing, Fudan University Shanghai Cancer Center, Shanghai, China.
Chong ChenDepartment of Nursing, Fudan University Shanghai Cancer Center, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Patients experience diverse symptoms during the oral intake rehabilitation period after esophagectomy, yet symptom interactions remain poorly understood. This study aimed to identify symptom clusters, core symptoms, and their relationships to inform targeted nursing interventions. Methods: In this cross-sectional study, 252 participants completed the Anderson Symptom Assessment Scale and the European Organization for Research and Treatment of Cancer quality of life questionnaire, specifically the esophageal-specific module (EORTC QLQ-OES18). Symptom clusters were derived via Principal Component Analysis (SPSS 26.0), and a network analysis (R4.3.1) was conducted to explore symptom centrality and interconnectedness. Results: Five symptom clusters emerged: reflux symptoms, unpleasant eating changes, low spirits symptoms, nerve damage symptoms, and energy deficiency symptoms. Distress (strength ​= ​4.878, betweenness ​= ​20, closeness ​= ​0.263) and trouble enjoying meals (strength ​= ​4.666, betweenness ​= ​28, closeness ​= ​0.258) were identified as core symptoms and with the highest bridge strength (distress: 3.400; trouble enjoying meals: 3.210). Patients experiencing these symptoms exhibited significantly greater weight loss (distress: 2.60 ​± ​2.52 vs. 1.68 ​± ​2.10 kg, Conclusions: Distress and trouble enjoying meals are not only core symptoms but also bridge symptoms. Future interventions targeting these two symptoms may be able to alleviate the overall symptoms and reduce weight loss during the oral intake rehabilitation period following esophagectomy.

Indexed as

Esophageal cancerEsophagectomyNetwork analysisOral intake rehabilitationSymptom management

Identifiers

PMID40485991
PMCPMC12142522

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.