Evidence map›Paper›PMID 40487045›Full record

ArticleRadiology case reports2025

An atypical cause of optic neuritis: Myelin oligodendrocyte glycoprotein antibody disease (MOGAD).

Mark A Colantonio, Danielle Sblendorio, Elizabeth Hart, Joshua Wiley

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mark A ColantonioDepartment of Medicine, West Virginia University, Morgantown, WV, USA.
Danielle SblendorioDepartment of Neurology, West Virginia University, Morgantown, WV, USA.
Elizabeth HartDepartment of Medicine, West Virginia University, Morgantown, WV, USA.
Joshua WileyDepartment of Medicine, West Virginia University, Morgantown, WV, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a novel, demyelinating disease presenting with optic neuritis, along with other central nervous pathologies. First implicated in 2007, it remains a rare disease, with a prevalence of roughly 1.3 per 1 million adults. We present a case of MOGAD in a young female presenting to our rural healthcare facility with endorsements of eye pain and blurred vision. Imaging revealed findings consistent with optic neuritis, as well as hyperintensities of her cerebrum and cervical spine. Distinguishing radiographic features from other neurological pathologies, including conus medullaris enhancement, were not present, highlighting the importance of considering the clinical picture as a whole. We aim to bring awareness to this rare disease, especially to those practitioners localized to a rural environment.

Indexed as

DemyelinationMagnetic resonance imagingMyelin oligodendrocyte glycoprotein antibody diseaseOptic neuritis

Identifiers

PMID40487045
PMCPMC12145056

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.