Evidence map›Paper›PMID 40487228›Full record

ArticleRegenerative therapy2025

The effect of l-lactide-ε-caprolactone copolymer membrane on alveolar bone preservation: A comparative study using the open healing approach.

Masayuki Takabayashi, Yoshio Yahata, Keisuke Handa, Moe Sandar Kyaw, Venkata Venkataih Suresh, Masahiro Saito

Abstract read
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In one paragraph

Article in Regenerative therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masayuki TakabayashiDivision of Operative Dentistry, Department of Ecological Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Yoshio YahataDivision of Operative Dentistry, Department of Ecological Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Keisuke HandaDivision of Molecular Biology and Oral Biochemistry, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaoka-cho, Yokosuka, Kanagawa 238-8580, Japan.
Moe Sandar KyawDivision of Operative Dentistry, Department of Ecological Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
Venkata Venkataih SureshDepartment of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, 162, Poonamallee High Rd, Velappanchavadi, Chennai, Tamil Nadu 600077, India.
Masahiro SaitoDivision of Operative Dentistry, Department of Ecological Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study evaluated the efficacy of a resorbable l-lactide-ε-caprolactone copolymer (PLCL) membrane in promoting epithelial healing and preserving alveolar bone morphology using the open healing approach (OHA), compared to conventional membranes. Methods: Extraction sockets in beagle dogs were filled with bone substitute material and covered with different membranes. Healing was assessed via histological analysis and micro-CT imaging. Results: The PLCL membrane reduced bone resorption and preserved alveolar bone morphology better than conventional membranes. Histological analysis showed excellent epithelial healing and notable bone formation. Conclusions: The PLCL membrane effectively prevents infection, supports epithelial healing, and preserves alveolar bone morphology in OHA procedures.

Indexed as

Alveolar bone lossPoly (lactic acid/caprolactone) bilayer membraneSocket preservationTooth extractionWound healing

Identifiers

PMID40487228
PMCPMC12141835

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.