Evidence map›Paper›PMID 40487628›Full record

ArticleWorld journal of diabetes2025

Single-nucleotide polymorphisms in genes involved in folate metabolism or selected other metabolites and risk for gestational diabetes mellitus.

Ting-Ting Zheng, Jia-He Liu, Wan-Tong Huang, Bo Hong, Di Wang, Chun-Yi Liu, Jie Zhang, Si-Si Li, Shao-Wei Wu, Qi Wang and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ting-Ting ZhengDepartment of Obstetrics and Gynecology, The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Jia-He LiuInstitute of Reproductive and Child Health, Peking University, Beijing 100191, China.
Wan-Tong HuangInstitute of Reproductive and Child Health, Peking University, Beijing 100191, China.
Bo HongDepartment of Obstetrics and Gynecology, Haidian Maternal and Child Health Care Hospital of Beijing, Beijing 100191, China.
Di WangInstitute of Reproductive and Child Health, Peking University, Beijing 100191, China.
Chun-Yi LiuInstitute of Reproductive and Child Health, Peking University, Beijing 100191, China.
Jie ZhangInstitute of Reproductive and Child Health, Peking University, Beijing 100191, China.
Si-Si LiInstitute of Reproductive and Child Health, Peking University, Beijing 100191, China.
Shao-Wei WuDepartment of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University Health Science Center, Xi'an 710000, Shaanxi Province, China.
Qi WangDepartment of Toxicology, School of Public Health, Peking University, Beijing 100191, China.
Lei ChenDepartment of Obstetrics and Gynecology, The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510515, Guangdong Province, China.
Lei JinInstitute of Reproductive and Child Health, Peking University, Beijing 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are conflicting results on the potential correlation between folic acid and gestational diabetes mellitus (GDM), and the correlation between genetic factors related to folic acid metabolism pathways and GDM remains to be revealed.

aimTo examine the association between single-nucleotide polymorphisms (SNPs) of enzyme genes in the folate metabolite pathway as well as that between GDM-related genes and risk for GDM.

methodsA nested case-control study was conducted with GDM cases (

resultsThe variation allele frequency of melatonin receptor 1B (

conclusionThis study does not find an association between SNPs of folate metabolic enzymes and risk for GDM. The G mutant allele of

Indexed as

Deoxyribonucleic acidFolateGeneGestational diabetes mellitusSingle nucleotide polymorphisms

Identifiers

PMID40487628
PMCPMC12142184

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.