Evidence map›Paper›PMID 40488049›Full record

ArticleACS omega2025

Organic-Inorganic Magnetic Nanoparticles Based on Magnetite Coated with Molecularly Imprinted Polymers for Drug Delivery Systems.

Sandra Ramírez-Rave, Leticia Antonio Gutiérrez, Iván D Rojas-Montoya, Ma Josefa Bernad-Bernad, Jesús Gracia-Mora

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandra Ramírez-RaveDepartamento de Química Inorgánica, Facultad de Química, UNAM, Avenida Universidad 3000, 04510 Ciudad de México, México.
Leticia Antonio GutiérrezDepartamento de Química Inorgánica, Facultad de Química, UNAM, Avenida Universidad 3000, 04510 Ciudad de México, México.
Iván D Rojas-MontoyaDepartamento de Química Inorgánica, Facultad de Química, UNAM, Avenida Universidad 3000, 04510 Ciudad de México, México.
Ma Josefa Bernad-BernadDepartamento de Farmacia, Facultad de Química, UNAM, Avenida Universidad 3000, 04510 Ciudad de México, México.
Jesús Gracia-MoraDepartamento de Química Inorgánica, Facultad de Química, UNAM, Avenida Universidad 3000, 04510 Ciudad de México, México.ORCID https://orcid.org/0000-0001-8067-1215

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New magnetic organic/inorganic hybrid nanoparticles were prepared by coating the magnetite surface with molecularly imprinted polymers of different monomers (methacrylic acid, itaconic acid, 1-vinylimidazole, 4-vinylpyridine). Magnetite was synthesized by coprecipitation, and polymeric coatings were induced by thermal heating and magnetic hyperthermia. The resultant nanocomposites were tested as Drug Delivery Systems (DDS) of 6-mercaptopurine (6-MP), displaying an interesting behavior depending on (a) the synthesis method used for their preparation and (b) the conditions employed for the release test. DDS based on methacrylic acid displayed the best performance in the release of 6-MP in all cases, but the rationalization of a magnetite MIP (molecularly imprinted polymer) system of this monomer enhanced the release yield by approximately 50% compared with the nonimprinted system (NIP) prepared with the same monomer. New MNP obtained are able to behave as DDS under magnetic hyperthermia with a moderate performance in contrast to the release in the absence of magnetic field.

Identifiers

PMID40488049
PMCPMC12138690

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.