Evidence mapPaperPMID 40488773Full record

ReviewPediatric radiology2025

Cardiac magnetic resonance imaging in the assessment of cardiac injury and toxicity from cancer-related chemotherapy.

Jason N Johnson, Tiffany L Berthod, Xiaoying Cai, M Jay Campbell, Anudeep K Dodeja, Chris G Goode, Kan N Hor, Hannah M Jacobs, Simon Lee, Yue-Hin Loke and 6 more

Abstract readReview
In one paragraph

Review in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jason N JohnsonThe University of Tennessee Health Science Center, Memphis, TN, USA. jjohn315@uthsc.edu.
Tiffany L BerthodDivision of Pediatric Cardiology, Connecticut Children's, 282 Washington Street, Hartford, CT, 06106, USA.
Xiaoying CaiSiemens Medical Solution USA Inc., New York, NY, USA.
M Jay CampbellDivision of Pediatric Cardiology, Duke University Medical Center, Durham, NC, USA.
Anudeep K DodejaDivision of Pediatric Cardiology, Connecticut Children's, 282 Washington Street, Hartford, CT, 06106, USA.
Chris G GoodeDepartment of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, TN, USA.
Kan N HorDivision of Pediatric Cardiology, Nationwide Children's Hospital, Columbus, OH, USA.
Hannah M JacobsDivision of Pediatric Cardiology, Nationwide Children's Hospital, Columbus, OH, USA.
Simon LeeHeart Center, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Yue-Hin LokeDivision of Pediatric Cardiology, Children's National Hospital, Washington, D.C., USA.
Raymond P LorenzoniDivision of Pediatric Cardiology, Connecticut Children's, 282 Washington Street, Hartford, CT, 06106, USA.
Cara E MorinDepartment of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Andrada R PopescuNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Jonathan H SoslowDivision of Pediatric Cardiology, Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, TN, USA.
Erin R TraskRadiology, Connecticut Children's, Hartford, CT, USA.
Olga H Toro-SalazarDivision of Pediatric Cardiology, Connecticut Children's, 282 Washington Street, Hartford, CT, 06106, USA. Otoro@connecticutchildrens.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A dedicated guideline to the evaluation of cardiovascular toxicity in pediatric cancer by cardiac magnetic resonance imaging (MRI) does not exist. Therefore, the aim of this document is to provide guidance in the utility, acquisition, and interpretation of cardiac MRI in childhood cancer survivors. We will focus on briefly defining cardiovascular toxicity in childhood cancer survivors and reviewing the key aspects of a detailed cardiac MRI study in a patient with acute versus chronic cardiovascular toxicity. We intend for this document to serve as a guideline on how to perform a cardiac MRI to evaluate cardiac toxicity based on a review of the current literature. There will be a review of a detailed cardiac MRI protocol (bi-ventricular volumes and mass, myocardial strain, tissue characterization, late gadolinium enhancement, and 4 Dimensional/4D flow) in the assessment of cardiovascular toxicity from cancer therapy. It is hoped that the availability of a standardized approach to cardiac MRI assessment in childhood cancer survivors improves cardiovascular care in this population.

Indexed as

Antineoplastic AgentsCardiotoxicityMagnetic Resonance ImagingNeoplasmsChildHumansAntineoplastic AgentsCancer survivorsCardiotoxicityChildMagnetic resonance imaging

Identifiers

PMID40488773
PMCPMC12594720

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.