ReviewJournal of endocrinological investigation2025
Obesity and obesity related disease in adulthood: the dark side of early life exposure to Environmental Chemical Disruptors.
Review in Journal of endocrinological investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Associations between urinary biomarkers of drinking-water disinfection byproducts and fasting plasma glucose: results from the TREE study.Journal of endocrinological investigation · 2026Article
- Perioperative inflammatory cytokines nursing screening test indicate the link between dysregulated lipid metabolism and reduced bone mineral density in obese osteoporosis patients: a retrospective study.BMC musculoskeletal disorders · 2026Article
- The Impact of High-Resolution LC-MS/MS Detected Environmental Exposures on Obesity: A Study of Cumulative Effects Through Statistical Modeling.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Precision nutrition targeting the gut microbiota for weight management: mechanisms and applications.Frontiers in microbiology · 2026Review
- Breastfeeding in a Polluted World: Perspective on the Properties of Breast Milk and the Need for Protection.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present review aims to summarize and collect data in support of the obesogenic theory to broaden knowledge regarding the intriguing relationship between exposure to environmental chemical disruptors (EDCs), obesity and obesity related diseases.
methodsA comprehensive search of the literature from 1990 to 2024 was performed in Pubmed using the word endocrine disruptor chemicals or obesogens and: adipose tissue, metabolic diseases, weight gain, gut microbiota.
resultsIn the past, genetic factors, an unbalanced diet and a sedentary lifestyle were considered the only risk factors for obesity development. On the other hand, recent studies described the obesogenic theory, suggesting that an interaction between exposure to EDCs with obesogenic activity, especially during early life development, and the endocrine system can play a key role in the greater susceptibility to the onset of obesity, not even excluding the involvement of the gut microbiota and its alterations.
conclusionsData collected show that there is a close link between environmental exposure to EDCs during early life of development and the onset of obesity and related dysmetabolic diseases that may occur later in life.
Indexed as
Identifiers
40488984What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.