Evidence map›Paper›PMID 40490274›Full record

Observational studyBMJ mental health2025

Intimate partner violence, traumatic brain injury and long-term mental health outcomes in midlife: the Drake IPV study.

Natalie D Jenkins, Craig W Ritchie, Karen Ritchie, Graciela Muniz Terrera, William Stewart, PREVENT Dementia Investigators

Abstract readObservational Study
In one paragraph

Observational study in BMJ mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalie D JenkinsUniversity of Glasgow, Glasgow, UK.
Craig W RitchieDepartment of Medicine, University of St Andrews, St Andrews, UK.
Karen RitchieINM Institut de Neurosciences de Montpellier, Montpellier, France.
Graciela Muniz TerreraDepartment of Social Medicine, Ohio University Heritage College of Osteopathic Medicine, Athens, Ohio, USA.
William StewartUniversity of Glasgow, Glasgow, UK william.stewart@glasgow.ac.uk.ORCID http://orcid.org/0000-0003-2199-2582
PREVENT Dementia Investigators

Funding

Data Coordinating CoreU54NS115322 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SMITH, DOUGLAS HAMILTON · 2019 to 2023
$9.2M
TBI: Uncovering Mechanisms of AD-like pathologyR01NS038104 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SMITH, DOUGLAS HAMILTON · 1999 to 2020
$7.6M
Transdisciplinary Research Accelerating Neuropathology Studies and Facilitating Open Research Methods in TBI (TRANSFORM-TBI)U01NS137500 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Edward Byung-Ha Lee, Douglas Hamilton Smith · 2024 to 2026
$5.8M
Neuropathological Characterization of 'CTE'R01NS094003 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Douglas Hamilton Smith, William Stewart · 2016 to 2026
$5.1M
NINDS NIH HHS R01 NS038104NINDS NIH HHS R01 NS094003NINDS NIH HHS U01 NS137500NINDS NIH HHS U54 NS115322
6 · The paper itself

Abstract

backgroundApproximately 30% of women experience intimate partner violence (IPV) in their lifetime, often with traumatic brain injury (TBI) exposure. Nevertheless, there has been limited research exploring lifelong brain health outcomes following IPV with TBI. To address this, we investigated the relationship between IPV, TBI and midlife mental health outcomes within an observational cohort study.

methodsPREVENT Dementia is a cohort study with participants recruited aged 40-59 years for longitudinal measures of brain health. Participants reporting histories of IPV-related physical abuse (IPV-PA) at study recruitment were identified and compared with control participants with no IPV-PA exposure regarding histories of TBI and prevalence of lifetime and ongoing mental health outcomes using standardised assessments.

resultsAmong 632 participants, 90 (14%) reported IPV-PA history. Compared with unexposed participants, history of IPV-PA was associated with higher TBI exposure, together with higher lifetime and ongoing diagnoses of depression, anxiety and sleep disorders, and post-traumatic stress disorder (PTSD) symptomology. Notably, the risk of ongoing and concurrent midlife mental health disorders remained despite IPV-PA exposure having ceased on average 27 years before assessment. History of TBI in individuals with IPV was associated with increased risk of ongoing PTSD symptomology and concurrent mental health outcomes.

conclusionsOur data confirm high TBI exposure among individuals with a history of IPV-PA, while also demonstrating that this population shows higher rates of ongoing adverse mental health outcomes in midlife, often decades after abuse. This work underlines the prevalence of IPV-PA and the necessity to consider TBI exposure and long-term brain health outcomes among this population.

Indexed as

Brain Injuries, TraumaticIntimate Partner ViolenceMental DisordersAdultCohort StudiesFemaleHumansLongitudinal StudiesMaleMental HealthMiddle AgedPrevalenceStress Disorders, Post-Traumaticanxiety disordersdepressiondepression & mood disorders

Identifiers

PMID40490274
PMCPMC12161325

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.