Evidence map›Paper›PMID 40490608›Full record

Trial reportEuropean journal of nutrition2025

Impact of a mineral enriched, fiber complex on glycaemic response and satiation in healthy adults: a double-blind, crossover intervention study.

Oana Ancu, Richard W A Mackenzie, Michael Patterson, Evone Dsilva, Gleb E Yakubov, Michael Haynes, Sofia Kolida, Christopher G Stephenson, Adele Costabile

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Oana AncuSchool of Life and Health Sciences, University of Roehampton, London, SW15 4 JD, UK.
Richard W A MackenzieInstitute of Cardio-Metabolic Medicine, Coventry University, University Hospital Coventry & Warwick NHS Trust, Coventry, CV15 FB, UK.
Michael PattersonSchool of Life and Health Sciences, University of Roehampton, London, SW15 4 JD, UK.
Evone DsilvaDivision of Food, Nutrition and Dietetics, School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
Gleb E YakubovDivision of Food, Nutrition and Dietetics, School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
Michael HaynesSchool of Life and Health Sciences, University of Roehampton, London, SW15 4 JD, UK.
Sofia KolidaOptiBiotix Health Plc, Innovation Centre, Innovation Way, Heslington, York, Y010 5DG, UK.
Christopher G StephensonOptiBiotix Health Plc, Innovation Centre, Innovation Way, Heslington, York, Y010 5DG, UK.
Adele CostabileSchool of Life and Health Sciences, University of Roehampton, London, SW15 4 JD, UK. adele.costabile@roehampton.ac.uk.ORCID http://orcid.org/0000-0003-3185-030X

Funding

Research Agreement LSC/2018/64 - Roehampton UniversityResearch Agreement Optibiotix Life SciencesResearch Agreement UK
6 · The paper itself

Abstract

purposeTo investigate the effects of a chromium-enriched glucomannan-fructooligosaccharide complex (SB) on glycaemic and insulin responses, satiation, and hunger biomarkers in healthy adults.

methodsUsing a double-blind, placebo-controlled, randomised crossover design, we assessed the acute impact of a single 3 g SB dose in 16 healthy adults (BMI 18.5-24.9 kg/m

resultsSBD intake significantly reduced the insulin concentration compared to dextrose alone at 45, 75, and 90 min post-intake. Additionally, SBD resulted in significantly greater fullness and a lower desire to eat at 75 min when compared to dextrose (p < 0.05). Although hunger increased over time for both interventions, SBD led to lower hunger, desire to eat, and food desire scores compared to dextrose at 150 min (p < 0.05). The viscosity of SB, even when combined with dextrose, was significantly higher compared to dextrose alone.

conclusionsThese novel findings suggest that SB can modulate insulin response and influence appetite regulation, highlighting its potential use in weight management strategies.

Indexed as

Blood GlucoseDietary FiberSatiationAdultChromiumCross-Over StudiesDouble-Blind MethodFemaleGlucose Tolerance TestHumansHungerInsulinMaleMannansMiddle AgedYoung Adult(1-6)-alpha-glucomannanBlood GlucoseChromiumDietary FiberInsulinMannansAppetite regulationDietary supplementsInsulin responseWeight management

Identifiers

PMID40490608
PMCPMC12148962

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.