Evidence map›Paper›PMID 40491960›Full record

ArticleiScience2025

Long read genome unravels MHC I genomic architecture, evolution, and diversity loss in

Marisol Domínguez, Enrique Celemín, Nikolai Gusev, Binia De Cahsan, Katja Havenstein, Bettina Mahler, Ralph Tiedemann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marisol DomínguezUnit of Evolutionary Biology/Systematic Zoology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Enrique CelemínUnit of Evolutionary Biology/Systematic Zoology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Nikolai GusevUnit of Evolutionary Biology/Systematic Zoology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Binia De CahsanGlobe Institute, University of Copenhagen, Copenhagen, Denmark.
Katja HavensteinUnit of Evolutionary Biology/Systematic Zoology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
Bettina MahlerIEGEBA, FCEN-UBA, Pabellón II, Ciudad Universitaria, Ciudad Autónoma de Buenos Aires 1428, Argentina.
Ralph TiedemannUnit of Evolutionary Biology/Systematic Zoology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The major histocompatibility complex (MHC) genes are vital for the adaptive immune response in vertebrates and are widely used in conservation genetics to represent adaptive variation. Accurate genotyping of MHC alleles is essential for effective conservation, particularly for endangered species like the yellow cardinal (

Indexed as

Evolutionary biologyGenomicsOrnithology

Identifiers

PMID40491960
PMCPMC12146618

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.