Evidence map›Paper›PMID 40491981›Full record

ArticleFood science & nutrition2025

Peimine Promotes Skin Wound Repair in Mice by Activating the Notch1 Signaling Pathway in Fibroblasts.

Peng Wu, Cheng Zhang, Congcong Wu, Junzhe Lang, Lili He

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Role of the Notch1 Signaling Pathway in the Pathogenesis and Treatment of Diabetic Foot: A Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peng WuDepartment of Orthopaedics The First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Cheng ZhangDepartment of Orthopaedics The First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Congcong WuDepartment of Orthopaedics The First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Junzhe LangDepartment of Orthopaedics The First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Lili HeDepartment of Dermatology The First Affiliated Hospital of Wenzhou Medical University Wenzhou China.ORCID https://orcid.org/0009-0000-6706-0890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the effects of peimine on cutaneous wound healing efficiency and tissue regeneration in murine models, while exploring its regulatory mechanisms through the Notch1 signaling pathway. Full-thickness circular skin defects (8-mm diameter) were surgically created on the dorsal surface of C57BL/6 mice, with subsequent daily topical administration of peimine at 1 and 4 mg · kg

Indexed as

healing rateNotch1peiminevascular regenerationwound healing

Identifiers

PMID40491981
PMCPMC12146499

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.