Evidence map›Paper›PMID 40492719›Full record

ArticlemSphere2025

Dynamics of amylopectin granule accumulation during the course of chronic

Aashutosh Tripathi, Ryan W Donkin, Joy S Miracle, Robert D Murphy, Matthew S Gentry, Abhijit Patwardhan, Anthony P Sinai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. mSphere of Influence:mSphere · 2025
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Aashutosh TripathiDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.ORCID 0000-0002-1356-656X
Ryan W DonkinDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Joy S MiracleDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Robert D MurphyDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Matthew S GentryDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, USA.
Abhijit PatwardhanF. Joseph Halcomb III, MD, Department of Biomedical Engineering, University of Kentucky College of Engineering, Lexington, Kentucky, USA.
Anthony P SinaiDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.ORCID 0000-0003-0821-5869

Funding

Brain Glycogen-Metabolism,Mechanisms, and Therapeutic PotentialR35NS116824 · NINDS · UNIVERSITY OF KENTUCKY · PI Matthew S. Gentry · 2020 to 2026
$8.2M
Quantitative Approaches for Drug Testing in Chronic Toxoplasmosis: Leveraging New Insights Into Bradyzoite Biology Within Tissue Cysts In VivoR01AI145335 · NIAID · UNIVERSITY OF KENTUCKY · PI PATWARDHAN, ABHIJIT R., SINAI, ANTHONY P. · 2019 to 2021
$1.1M
Role of amylopectin granules in chronic toxoplasmosis, an HIV-AIDS defining infectionR21AI150631 · NIAID · UNIVERSITY OF KENTUCKY · PI SINAI, ANTHONY P. · 2020 to 2021
$421k
National Institute of Allergy and Infectious Diseases R21AI150631National Institute of Allergy and Infectious Diseases RO1AI145335National Science Foundation Graduate Research Fellowship Program 1247392NIAID NIH HHS R01 AI145335NIAID NIH HHS R21 AI150631NINDS NIH HHS R35 NS116824
6 · The paper itself

Abstract

The contribution of amylopectin granules (AG), a branched chain storage homopolymer of glucose, to the maintenance and progression of the chronic

Indexed as

AmylopectinCytoplasmic GranulesToxoplasmaToxoplasmosisAnimalsMiceMitochondriaPersistent InfectionAmylopectinamylopectinbradyzoitechronic infectionmitochondrial metabolismrestriction checkpointToxoplasma gondii

Identifiers

PMID40492719
PMCPMC12306163

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.