Evidence map›Paper›PMID 40494962›Full record

ArticleNature reviews. Rheumatology2025

2023 International Rome consensus for the nomenclature of Sjögren disease.

Manuel Ramos-Casals, Alan N Baer, María Del Pilar Brito-Zerón, Katherine M Hammitt, Coralie Bouillot, Soledad Retamozo, Alison Mackey, David Yarowsky, Breck Turner, Jaime Blanck and 39 more

Abstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in Nature reviews. Rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. [Diagnostics of Sjögren's disease].Zeitschrift fur Rheumatologie · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Review
  15. Inflammasomes in Sjögren's Disease: Exploring the Therapeutic Value.International journal of molecular sciences · 2026
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors.

Manuel Ramos-Casals *Department of Autoimmune Diseases, ICMiD, Hospital Clínic, Barcelona, Spain.
Alan N Baer *Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. alanbaer@jhmi.edu.ORCID http://orcid.org/0000-0001-8344-013X
María Del Pilar Brito-ZerónDepartment of Internal Medicine, Hospital CIMA Sanitas, Barcelona, Spain.
Katherine M HammittSjögren's Foundation, Reston, VA, USA.ORCID http://orcid.org/0000-0002-5080-597X
Coralie BouillotSjögren Europe, Gland, Switzerland.ORCID http://orcid.org/0009-0003-8021-2539
Soledad RetamozoDepartment of Rheumatology, Hospital Quiron Salud de Barcelona, Barcelona, Spain.
Alison MackeyDepartment of Linguistics, Georgetown University, Washington, DC, USA.
David YarowskyDepartment of Computer Science, Johns Hopkins University, Baltimore, MD, USA.
Breck TurnerWelch Medical Library, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jaime BlanckWelch Medical Library, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-7235-0857
Benjamin A FisherRheumatology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.ORCID http://orcid.org/0000-0003-4631-549X
Esen K AkpekOcular Surface Disease and Dry Eye Clinic, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Chiara BaldiniDepartment of Clinical and Experimental Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy.
Hendrika BootsmaRheumatology and Clinical Immunology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Simon J BowmanRheumatology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Thomas DörnerDepartment of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, and Deutsches Rheumaforschungszentrum, Berlin, Germany.ORCID http://orcid.org/0000-0002-6478-7725
Leslie LaingDepartment of Prosthodontics, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
Scott M LiebermanDivision of Rheumatology, Allergy, and Immunology, Stead Family Department of Paediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Xavier MarietteDepartment of Rheumatology, Université Paris-Saclay, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, Paris, France.
Stephen C PflugfelderDepartment of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.
Vidya SankarDivision of Oral Medicine, Department of Diagnostic Sciences, Tufts University School of Dental Medicine, Boston, MA, USA.
Antoni Sisó-AlmirallDepartment of Medicine, University of Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0001-9832-2689
Athanasios G TzioufasDepartment of Pathophysiology, School of Medicine, University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0001-6666-8642
Juan-Manuel AnayaUniversidad de la Costa, Barranquilla, Colombia.ORCID http://orcid.org/0000-0002-6444-1249
Berkan ArmağanClinic of Rheumatology, Ankara Bilkent City Hospital, Ankara, Turkey.
Michele BombardieriCentre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK.
Steven CarsonsDivision of Rheumatology, Allergy and Immunology, Department of Medicine, NYU Grossman Long Island School of Medicine, Mineola, NY, USA.
Salvatore de VitaDivision of Rheumatology, Azienda Sanitaria Universitaria Friuli Centrale, Santa Maria della Misericordia Hospital, Udine, Italy.
Robert I FoxScripps Memorial Hospital and Research Foundation, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6222-7954
Roberto GerliRheumatology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Roberto GiacomelliClinical and research section of Rheumatology and Clinical Immunology, Fondazione Policiclinico Campus Biomedico, Rome, Italy.
Jacques Eric GottenbergDepartment of Rheumatology, Centre de Référence National pour les Maladies Autoimmunes Systémiques Rares, IBMC, CNR, UPR 3572, University of Strasbourg, Strasbourg, France.
Gabriela Hernández-MolinaDepartment of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Roland JonssonBroegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway.
Aike KruizeDepartment of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Seung-Ki KwokDivision of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Xiaomei LiDepartment of Rheumatology and Immunology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Sara S McCoyDepartment of Medicine, University of Wisconsin School of Medicine and Health, Madison, WI, USA.ORCID http://orcid.org/0000-0002-5293-4185
Wan-Fai NgTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Peter OlssonDepartment of Clinical Sciences, Malmö, Rheumatology, Lund University, Malmö, Sweden.
Maureen RischmuellerRheumatology Department, The Queen Elizabeth Hospital and University of Adelaide, South Australia, Adelaide, Australia.
Alain SarauxUniversité de Bretagne Occidentale, Inserm (U1227), LabEx IGO, Brest, France.
R Hal ScofieldArthritis & Clinical Immunology, Oklahoma Medical Research Foundation; Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Valéria ValimHospital Universitário Cassiano Antônio Moraes (Hucam), Programa de Pós-graduação em Saúde Coletiva (PPGSC), Universidade Federal do Espírito Santo (Ufes), Vitória, Espírito Santo, Brazil.
Claudio VitaliConsultant in Rheumatology, Istituto Clinico 'Mater Domini', Castellanza, Italy.
Frederick VivinoPenn Presbyterian Medical Center, University of Pennsylvania, Philadelphia, PA, USA.
Marie Wahren-HerleniusDivision of Rheumatology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-0915-7245
Haralampos M MoutsopoulosAcademy of Athens, Athens, Greece.
International Task Force on Nomenclature of Sjögren Disease

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nomenclature for the disease widely known as Sjögren syndrome has proven unsatisfactory. Patients have perceived 'syndrome' as indicative of a vague collection of symptoms, prompting the Sjögren's Foundation to abandon the term. Furthermore, the traditional distinction between 'primary' and 'secondary' forms fails to account for the complex interplay between overlapping autoimmune diseases. Following a bibliometric analysis, systematic literature review and a Delphi consensus process with equal involvement of professional and patient representatives, five recommendations are now issued. First, the term 'Sjögren disease' should replace 'Sjögren syndrome'. Second, the acronym 'SjD' should be used as an abbreviation for 'Sjögren disease'. Third, the descriptor 'associated' should be used in lieu of 'secondary' for Sjögren disease occurring in association with a second systemic autoimmune disease for which classification criteria are fulfilled. Fourth, Sjögren disease is the preferred terminology in common parlance and in clinical diagnosis, without differentiation as to primary and associated forms. Fifth, the differentiation between primary and associated Sjögren is recommended for scientific studies to define a homogeneous population. In conclusion, the consensus endorses 'Sjögren disease' as the official nomenclature to acknowledge the distinct pathogenesis of this disorder and to improve clarity in both clinical practice and research.

Indexed as

Sjogren's SyndromeTerminology as TopicDelphi TechniqueHumans

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.