Evidence map›Paper›PMID 40495238›Full record

ArticleReproductive biology and endocrinology : RB&E2025

A multidisciplinary approach to weight management and reproductive care: a retrospective cohort study on weight loss through personalized and patient-centered care.

Samantha Schon, Jocelyn Spizman, Daria Stelmak, Mark Chames, Stacey Pilarz, Jamila Abdur-Rahman, Charley Jiang, Amal Othman, Marie Menke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive biology and endocrinology : RB&E, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samantha SchonDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Michigan, L4000 University Hospital South, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA. sschon@med.umich.edu.
Jocelyn SpizmanUniversity of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI, 48109, USA.
Daria StelmakUniversity of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI, 48109, USA.
Mark ChamesDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Michigan, L4000 University Hospital South, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.
Stacey PilarzNutrition Services, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.
Jamila Abdur-RahmanDepartment of Social Work, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.
Charley JiangDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Michigan, L4000 University Hospital South, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.
Amal OthmanDepartment of Family Medicine, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.
Marie MenkeDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Michigan, L4000 University Hospital South, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a highly prevalent chronic disease with a significant and complex impact on reproduction. National guidelines recommend weight loss prior to pregnancy for patients with obesity to mitigate complications and increase fertility; however, targeted, personalized interventions are limited. The objectives of this study are to describe the implementation of a multidisciplinary program designed specifically for women with reproductive disorders and obesity and to report differences in baseline characteristics and weight loss outcomes between women willing vs. not willing to defer pregnancy attempts to focus on weight loss.

methodsRetrospective cohort study at a university multidisciplinary program for women with reproductive disorders and obesity. All participants from program initiation (November 2021) through July 2023 were included in the analysis. Primary outcome was percent body weight loss at 3 months. Secondary outcomes included weight loss at 6 months and achievement of > 5% and > 10% weight loss at each time point.

resultsA total of 237 participants were included in the analysis. The majority of participants (88.2%) desired pregnancy. 63.2% of participants who desired pregnancy were willing to postpone pregnancy attempts/fertility treatments so that they could focus on weight loss for at least 3 months. Participants willing to defer pregnancy attempts achieved a significantly greater weight loss at 3 months compared to those who continued pregnancy attempts (mean - 4.8% vs. -2.5%, p = 0.004) and were more likely to achieve > 10% body weight loss at 3 months (14.0% vs. 2.20%, p = 0.031). Those who achieved > 5% weight loss by 6 months were more likely to achieve pregnancy within the first 6 months of trying to conceive (34.1% vs. 7.7%, p = 0.004).

conclusionsWe describe the development and implementation of a multidisciplinary program for women with reproductive disorders and obesity seeking weight management. An individualized approach to weight management and reproductive care results in clinically significant weight loss especially among women willing to defer pregnancy attempts and focus on weight loss for at least 3 months.

trial registrationClinical trial number: Not applicable.

Indexed as

ObesityPatient-Centered CarePrecision MedicineWeight LossWeight Reduction ProgramsAdultCohort StudiesFemaleHumansPatient Care TeamPregnancyRetrospective StudiesAnti-obesity medicationInfertilityObesityPCOSReproductionWeight lossWeight navigation

Identifiers

PMID40495238
PMCPMC12150559

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.