ReviewClinical, cosmetic and investigational dermatology2025
Advances in Genetic Polymorphism Research in Rosacea: Mechanisms and Clinical Implications.
Review in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Beyond the boundaries of pigmentation and inflammation: understanding the mechanistic basis of melasma-rosacea comorbidity.Frontiers in medicine · 2026Review
- Exploring Immune-Related Gene and Mechanisms in Rosacea Through Transcriptome Analysis and Mendelian Randomization.BioMed research international · 2026Article
- Unraveling the Mechanism of Cuochuangling Pills in Rosacea Treatment: An Integrated Approach Combining Network Pharmacology, Bioinformatics, and Experimental Validation.Clinical, cosmetic and investigational dermatology · 2026Article
- Current Trends and Future Insights on Rosacea Treatment: A Bibliometric Analysis.Clinical, cosmetic and investigational dermatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rosacea is a chronic inflammatory skin disease primarily affecting the central region of the face. Typical manifestations include erythema, papules, or pustules on the cheeks, glabella, chin, and nose, with some patients experiencing ocular involvement. The pathogenesis of this disease is influenced by both polygenic inheritance and environmental factors, with abnormalities in innate immunity and neurovascular regulation playing a leading role. Recent genetic studies have identified several key genes, including Human Leukocyte Antigen (HLA), Toll-Like Receptor 2 (TLR2), Interleukin-17 (IL-17), Cathelicidin Antimicrobial Peptide (CAMP), and others, that are closely associated with rosacea onset and progression. This review summarized recent advances in rosacea-related genetic researches, aiming to reveal the genetic basis of the disease and provide support for early intervention and precision management of high-risk populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.