ReviewCancer reports (Hoboken, N.J.)2025
Association Between Maternal Diet During Pregnancy and the Risk of Childhood Acute Lymphoblastic Leukemia. An Overview.
Review in Cancer reports (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Regulatory Effects of Coffee/Chlorogenic Acid and Tea/Epigallocatechin-3-Current issues in molecular biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundThe effect of maternal habits during pregnancy has been studied to determine their association with the risk of childhood acute lymphoblastic leukemia (ALL).
aimTo synthesize current evidence on the association between maternal diet during pregnancy and the risk of childhood ALL.
methodsOverview of Systematic reviews (SRs) published until September 2023 were searched in MEDLINE (Pubmed), EMBASE, SCOPUS, Web of Science, and LILACS databases. Effect estimates and meta-aggregate analysis results are presented according to maternal exposure subgroups: (I) alcohol; (II) animal protein; (III) coffee; (IV) fruits and vegetables consumption; and (V) folic acid supplementation. The risk of bias was assessed independently by two authors using the AMSTAR II tool. PROSPERO protocol CRD42023462391.
resultsThirteen SRs were included; of these, according to the AMSTAR II tool, three were graded as high-quality, three as moderate-quality, five as low-quality, and two as critically low-quality reviews. The inclusion of meat (fish), fruits, and vegetables in the diet during pregnancy, as well as folic acid supplementation, seems to have a protective effect against the development of childhood ALL. In contrast, the daily frequency and amount of coffee consumption during pregnancy could influence the development of this type of cancer in the pediatric population. We did not find enough evidence supporting the association of alcohol as a risk factor of childhood ALL.
conclusionThe low certainty of the evidence found makes it impossible to establish clear associations between maternal exposure during pregnancy to any of the five nutritional factors here evaluated and the development of childhood ALL.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.