Evidence map›Paper›PMID 40498346›Full record

ArticleLangenbeck's archives of surgery2025

Safety and efficacy of the neuroform EZ stent for treating intracranial atherosclerotic stenosis in the posterior circulation: a comparative study of pre-procedure and post-procedure outcomes.

Kaimin Xiao, Rongxin He, Hongmei Chen, Ping Liu, Jiao Wu, Cai Zhong, Liang Zhong, Heling Chu, Yuping Tang, Li Chen and 1 more

Abstract readComparative Study
In one paragraph

Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kaimin Xiao *Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Rongxin He *Department of Neurology, The Affiliated Minzu Hospital of Guangxi medical university, Nanning, China.
Hongmei ChenDepartment of Neurology, People's Hospital of Ganxian District, Ganzhou, China.
Ping LiuChengdu University of Traditional Chinese Medicine, Chengdu, China.
Jiao WuChengdu University of Traditional Chinese Medicine, Chengdu, China.
Cai ZhongDepartment of Neurology, The Affiliated Minzu Hospital of Guangxi medical university, Nanning, China.
Liang ZhongDepartment of Neurology, The Affiliated Minzu Hospital of Guangxi medical university, Nanning, China.
Heling ChuDepartment of Gerontology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Yuping TangDepartment of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Li ChenDepartment of Neurology, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Yu LanDepartment of Neurology, The Affiliated Minzu Hospital of Guangxi medical university, Nanning, China. lanyu5915@163.com.

Funding

Major Science and Technology Special Project of Sichuan Provincial Department of Science and Technology No.2022ZDZX0022Science and Technology Department of Sichuan Province No. 2022YFS0618
6 · The paper itself

Abstract

backgroundTreatment options for intracranial atherosclerotic stenosis (ICAS) are limited, but endovascular intervention has gained increasing attention in recent years.

aimTo evaluate the safety and efficacy of the Neuroform EZ stent for treating ICAS in the posterior circulation. MATERIAL &

methodsPatients' (n = 50) eligibility depended on ICAS with severe stenosis (≥ 70%) in the intracranial segment of the vertebral artery or basilar artery shown by cerebral angiography. General information of the participants were recorded, Adverse events during the perioperative period were observed, including in-stent thrombosis, postoperative hyperperfusion, stroke, and mortality. Before the procedure, neurological deficits (NIHSS score) and neurological recovery (mRS score) were recorded at 12 months postoperatively. The degree of vascular stenosis was evaluated prior to and following the procedure, and in-stent restenosis (ISR) was recorded at 12 months post-operation.

resultsFifty-two stents were successfully placed in 50 patients, followed by standardized medication. Angiographic follow-up was completed 12-months postoperatively, and there was only one case of ISR (4.35%) was observed. Postoperative stenosis of responsible vessel was significantly relieved (77.98 ± 7.69 vs. 33.85 ± 9.11), with statistically significant differences (P < 0.01). The extent of neurological deficits and effects on daily living activities at 12 months postoperatively exhibited significant improvements, as evidenced by NIHSS scores (2.40 ± 1.37 vs. 0.82 ± 0.77) and mRS scores ≤ 2 (82.0% vs. 98.0%) (P < 0.01). Cerebral perfusion improved, with no significant perioperative complications.

conclusionsThe Neuroform EZ stent is a safe and effective treatment approach for ICAS in the posterior circulation.

Indexed as

Endovascular ProceduresIntracranial ArteriosclerosisStentsVertebrobasilar InsufficiencyAgedCerebral AngiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative ComplicationsReoperationRetrospective StudiesTreatment OutcomeIntracranial atherosclerotic stenosisNeuroform EZ stentPosterior circulation

Identifiers

PMID40498346
PMCPMC12158830

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.