Evidence map›Paper›PMID 40500159›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Varicella Zoster Virus Vasculopathy Leading to a Recurrent Cerebral Infarction: Differential Treatment Responses Between Stenosis and Occlusion.

Hideyuki Shimizu, Kenichi Sakuta, Motohiro Okumura, Yasuyuki Iguchi

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hideyuki ShimizuDepartment of Neurology, The Jikei University School of Medicine, Japan.
Kenichi SakutaDepartment of Neurology, The Jikei University School of Medicine, Japan.
Motohiro OkumuraDepartment of Neurology, The Jikei University School of Medicine, Japan.
Yasuyuki IguchiDepartment of Neurology, The Jikei University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella zoster virus (VZV) infection can cause vasculopathy and stroke; however, the response of VZV-induced vasculopathy to treatment is still not well understood. We herein report the case of a 41-year-old man with a recurrent cerebral infarction following herpes zoster infection. The patient presented with a visual field disturbance and a history of myelodysplastic syndrome and chronic kidney disease. Magnetic resonance imaging revealed multiple vascular stenoses and occlusions. Despite initial antiviral and steroid therapy, his condition worsened and he required additional treatment. Vessel stenosis responded well to treatment, whereas occlusion did not. An early diagnosis and prompt treatment of VZV-induced vasculopathy are crucial for preventing irreversible vascular damage.

Indexed as

Antiviral AgentsCerebral InfarctionHerpes ZosterSteroidsVascular DiseasesAdultConstriction, PathologicDiagnosis, DifferentialHumansMagnetic Resonance ImagingMaleRecurrenceTreatment OutcomeAntiviral AgentsSteroidscerebral infarctionintracranial artery occlusionintracranial artery stenosisvaricella zoster virusvasculopathy

Identifiers

PMID40500159
PMCPMC12804442

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.