Evidence map›Paper›PMID 40501733›Full record

ArticlebioRxiv : the preprint server for biology2025

Precise MRI-Histology Coregistration of Paraffin-Embedded Tissue with Blockface Imaging.

Yixin Wang, William Ho, Istvan N Huszar, Phillip DiGiacomo, Hossein Moein Taghavi, Lee Tao, Matthew Choi, Nhu Nguyen, Samantha Leventis, David B Camarillo and 8 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Yixin WangDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
William HoDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
Istvan N HuszarAthinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Boston, MA, USA.
Phillip DiGiacomoDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
Hossein Moein TaghaviDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
Lee TaoDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
Matthew ChoiDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
Nhu NguyenDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
Samantha LeventisDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
David B CamarilloDepartment of Bioengineering, Stanford University, Stanford, CA, USA.
Philipp SchlömerInstitute of Neuroscience and Medicine (INM-1), Forschungszentrum Jülich GmbH, Jülich, Germany.
Markus AxerInstitute of Neuroscience and Medicine (INM-1), Forschungszentrum Jülich GmbH, Jülich, Germany.
Shao WeiDepartment of Electrical & Computer Engineering, University of Florida, Gainesville, FL, USA.
Mirabela RusuDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
Inma CobosDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.
Jeff NirschlDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.
Marios GeorgiadisDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.
Michael ZeinehDepartment of Radiology, Stanford School of Medicine, Stanford, CA, USA.

Funding

Iron as an Imaging Biomarker for Inflammation in ADR01AG061120 · NIA · STANFORD UNIVERSITY · PI ZEINEH, MICHAEL M · 2019 to 2023
$3.5M
Quantifying myelin degeneration in ADR03AG083702 · NIA · STANFORD UNIVERSITY · PI GEORGIADIS, MARIOS · 2024 to 2024
$305k
NIA NIH HHS R01 AG061120NIA NIH HHS R03 AG083702
6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) provides 3D spatial information on tissue, yet it lacks at the molecular level. In contrast, histology provides cellular and molecular information, but it lacks the 3D spatial context and direct

Indexed as

BiomarkersBlockface imagingCoregistrationNeurodegenerative diseaseUltra-high-resolution MRIVolumetric histology

Identifiers

PMID40501733
PMCPMC12157374

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.