Evidence map›Paper›PMID 40502027›Full record

ArticlebioRxiv : the preprint server for biology2025

Persistently increased expression of PKMzeta and unbiased gene expression profiles identify hippocampal molecular traces of a long-term active place avoidance memory and 'shadow' proteins.

Jiyeon Han, Alejandro Grau-Perales, Rayna M Harris, Hsin-Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C Sacktor, Stefano Martiniani, Hans A Hofmann, Andre A Fenton

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Jiyeon HanCenter for Neural Science, New York University, New York, NY 10003, United States; Center for Soft Matter Physics, Department of Physics, New York University, New York, NY 10003, United States.
Alejandro Grau-PeralesCenter for Neural Science, New York University, New York, NY 10003, United States.
Rayna M HarrisDepartment of Integrative Biology and Institute for Neuroscience, The University of Texas. Austin, Austin, TX 78712, United States.
Hsin-Yi KaoCenter for Neural Science, New York University, New York, NY 10003, United States.
Asit PalCenter for Soft Matter Physics, Department of Physics, New York University, New York, NY 10003, United States; Simons Center for Computational Physical Chemistry, Department of Chemistry, New York University, New York, NY 10003, United States.
Juan Marcos AlarconDepartment of Pathology. State University of New York, Downstate Health Sciences University, Brooklyn, NY 11203, United States.
Todd C SacktorDepartments of Physiology and Pharmacology, Anesthesiology, and Neurology, State University of New York, Downstate Health Sciences University, Brooklyn, NY 11203, United States.
Stefano MartinianiCenter for Neural Science, New York University, New York, NY 10003, United States; Center for Soft Matter Physics, Department of Physics, New York University, New York, NY 10003, United States; Simons Center for Computational Physical Chemistry, Department of Chemistry, New York University, New York, NY 10003, United States; Courant Institute of Mathematical Sciences, New York University, New York, NY 10012, United States.
Hans A HofmannDepartment of Integrative Biology and Institute for Neuroscience, The University of Texas. Austin, Austin, TX 78712, United States.ORCID 0000-0002-3335-330X
Andre A FentonCenter for Neural Science, New York University, New York, NY 10003, United States; Neuroscience Institute at the New York University Langone Medical Center, New York, NY 10016, United States.ORCID 0000-0002-5063-1156

Funding

Molecular mechanisms of memory maintenance and dysfunction in neural circuitsR01MH115304 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI FENTON, ANDRE ANTONIO, SACKTOR, TODD C · 2018 to 2022
$4.1M
Towards a critical test of the synaptic plasticity and memory hypothesisR01MH132204 · NIMH · NEW YORK UNIVERSITY · PI ANDRE ANTONIO FENTON · 2023 to 2026
$2.5M
NIMH NIH HHS R01 MH115304NIMH NIH HHS R01 MH132204
6 · The paper itself

Abstract

Long-term memory formation transiently activates Ca

Indexed as

engramgene co-expression networksimmunohistochemistrytranscriptometrisynaptic pathway

Identifiers

PMID40502027
PMCPMC12154581

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.