Evidence map›Paper›PMID 40502621›Full record

ArticleAtherosclerosis plus2025

Fucosterol exerts an anti-atherosclerotic action via NF-κB and p38/Erk MAPK signaling pathways.

Tiancheng Liu, Mengli Zhang, Xian Wu, Zhenxing Liu, Huan Peng, Feng Gui, Wen Xiong, Qijuan Liu, Guojun Du, Bo Liu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Atherosclerosis plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tiancheng LiuDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Mengli ZhangDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Xian WuDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Zhenxing LiuDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Huan PengDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Feng GuiDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Wen XiongDepartment of Emergency, Jingchu University of Technology Affiliated Central Hospital, Jingmen, 448001, China.
Qijuan LiuDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Guojun DuDepartment of Emergency, Jingchu University of Technology Affiliated Central Hospital, Jingmen, 448001, China.
Bo LiuDepartment of Urology, Jingchu University of Technology Affiliated Central Hospital, Jingmen, 448001, China.
Chenchen ZhangICU: Department of Intensive Care Union, Jingchu University of Technology Affiliated Central Hospital, Jingmen, 448001, China.
Junfeng MaDepartment of Emergency, Jingchu University of Technology Affiliated Central Hospital, Jingmen, 448001, China.
Quan YuanDepartment of Anesthesiology, Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, 430000, China.
Wei LiDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Zhen ChenDepartment of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fucosterol is a sterol isolated from brown algae and has various biological properties, such anti-inflammatory and antidiabetic effects. In this study, we investigated the anti-atherosclerosis effects of fucosterol Methods: ApoE Results: Fucosterol reduced atherosclerotic plaques and lipid levels in apoE Conclusion: The current investigation revealed that fucosterol attenuates atherosclerotic plaques in apoE

Indexed as

AtherosclerosisEndothelial cellsFucosterolInflammationOxidative stress

Identifiers

PMID40502621
PMCPMC12152500

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.