Evidence map›Paper›PMID 40503362›Full record

ArticleWorld journal of stem cells2025

Potential of mesenchymal stem cell-derived exosomes in the treatment of androgenetic alopecia.

Ramya Lakshmi Rajendran, Byeong-Cheol Ahn, Prakash Gangadaran

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of stem cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ramya Lakshmi RajendranBK21 FOUR KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, Department of Biomedical Sciences, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
Byeong-Cheol AhnBK21 FOUR KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, Department of Biomedical Sciences, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
Prakash GangadaranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes are derived from various cell types, including mesenchymal stem cells (MSCs), and play a crucial role in cellular communication, significantly influencing tissue repair and regeneration and facilitating the healing process. Thus, insights into the functions of exosomes present novel opportunities in regenerative therapy. This article aims to discuss the promising potential of exosomes derived from human adipose-derived MSCs in treating androgenetic alopecia. This study aims to highlight how exosomes derived from human adipose-derived MSCs enhance dermal papilla cell proliferation through the Wnt/β-catenin pathway, counteracting the effects of excessive dihydrotestosterone and offering a novel approach for treating androgenetic alopecia.

Indexed as

Dermal papilla cellExosomeHair regrowthMesenchymal stem cellsWnt/β-catenin

Identifiers

PMID40503362
PMCPMC12149797

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.