Evidence mapPaperPMID 40504280Full record

Observational studyNeurosurgical review2025

Clinical characteristics and management of cerebral developmental venous anomalies accompanied with cavernous malformation.

Jiasheng Pei, Qizuan Chen, Huijian Zhang, Liangfeng Wei, Shousen Wang

Abstract readObservational Study
In one paragraph

Observational study in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiasheng PeiDepartment of Neurosurgery, The 900th Hospital, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350025, China.
Qizuan ChenDepartment of Neurosurgery, The 900th Hospital, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350025, China.
Huijian ZhangDepartment of Neurosurgery, The 900th Hospital, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350025, China.
Liangfeng WeiDepartment of Neurosurgery, The 900th Hospital, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350025, China.
Shousen WangDepartment of Neurosurgery, The 900th Hospital, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350025, China. wshsen1965@126.com.

Funding

Fujian Provincial Department of Science and Technology 2019Y9045
6 · The paper itself

Abstract

Developmental venous anomalies (DVAs) are common cerebral vascular anomalies that are frequently accompanied by cavernous malformations (CM), with mixed research on whether DVAs increase or decrease the risk of CM bleeding. This retrospective observational study aimed to investigate the clinical characteristics and management of DVAs accompanied by CMs. This study involved the clinical data of all patients with DVAs accompanied with CM from January 2013 to December 2023. A total of 14 patients aged 16-62 years (42.86 ± 14.56), were followed up for 10 to 150 months (53.57 ± 39.15). Twelve patients had a single CM, and two patients had multiple CMs. Nine patients did not experience bleeding, most patients showed no symptom aggravation throughout clinical observation or conservative treatment. Five patients with hemorrhage near the DVAs of the posterior cranial fossa experienced headache or focal neurological dysfunction. Two patients underwent surgery, and three obtained conservative treatment without new severe neurological dysfunction. Multiple de novo CMs formed after hemorrhage in two cases. Hemorrhage around the posterior fossa DVA may be an early signal of de novo CM.

Indexed as

Cerebral VeinsHemangioma, Cavernous, Central Nervous SystemIntracranial Arteriovenous MalformationsAdolescentAdultFemaleHumansMaleMiddle AgedNeurosurgical ProceduresRetrospective StudiesYoung AdultCerebral cavernous malformationCerebral venous malformationCerebrovascular malformationMagnetic resonance imagingSurgical treatment

Identifiers

PMID40504280
PMCPMC12162766

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.