Evidence map›Paper›PMID 40504568›Full record

ArticleTranslational vision science & technology2025

A Method for Visualizing Corneal Dynamics Through Pixel Intensity Tracking.

Ana R Arizcuren, Alejandra Consejo

Abstract read
In one paragraph

Article in Translational vision science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ana R ArizcurenAragon Institute for Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.
Alejandra ConsejoAragon Institute for Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To develop a methodology for analyzing dynamic corneal images using pixel intensity tracking and hue, saturation, and value (HSV) color space transformation, aiming to quantify and visually interpret corneal responsiveness to mechanical stimulation. Methods: This study utilized the OCULUS Corvis ST device to obtain dynamic corneal images from two subject groups (young and older individuals). To ensure accurate pixel tracking, segmentation and registration techniques were implemented. To counteract potential biases due to alterations in curvature and eye retraction caused by the air-puff mechanical stimulus, the last 30 frames available post-stimulus were used for analysis. Pixel intensity tracking calculations were then performed in the frequency domain to compute H, S, and V values for each pixel within the overall region of interest. Additionally, corneal biomechanical parameters from the Corvis ST were extracted to examine their relationship with HSV values. Results: The HSV transformation provided a quantitative visual interpretation of corneal dynamics, with reddish vibrant areas indicating higher responsiveness to mechanical stimulation and dull blue areas indicating lower responsiveness. Additionally, significant differences were found between the young and older groups in each of the three HSV channels (all P < 0.001). Four biomechanical parameters showed statistically significant differences between groups (P < 0.05), but no statistically significant correlation with HSV values was found. Conclusions: The HSV methodology effectively visualizes and quantifies corneal responsiveness to mechanical stimulation, offering a new approach for assessing corneal dynamics. Translational Relevance: HSV color space analysis has the potential to enhance the diagnosis and management of conditions in which corneal dynamics are affected.

Indexed as

CorneaImage Processing, Computer-AssistedAdultAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedYoung Adult

Identifiers

PMID40504568
PMCPMC12169463

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.