Evidence map›Paper›PMID 40504769›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Zinc-mediated Inhibition of Soluble Epoxide Hydrolase Promotes Pulmonary Hypertension.

Daniel Simoes de Jesus, Stanley Buffonge, Giancarlo Abis, Roberto Buccafusca, Reshma Baliga, Helen R Warren, Adrian Hobbs, Clemens Ruppert, Astrid Weiss, Ralph T Schermuly and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Zinc-mediated Inhibition of Soluble Epoxide Hydrolase Promotes Pulmonary Hypertension.American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Daniel Simoes de JesusWilliam Harvey Research Institute and.
Stanley BuffongeWilliam Harvey Research Institute and.
Giancarlo AbisRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London, United Kingdom; and.
Roberto BuccafuscaSchool of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom.
Reshma BaligaWilliam Harvey Research Institute and.
Helen R WarrenWilliam Harvey Research Institute and.
Adrian HobbsWilliam Harvey Research Institute and.
Clemens RuppertUniversities of Giessen & Marburg Lung Center Giessen Biobank and.
Astrid WeissDepartment of Internal Medicine, Member of the German Center for Lung Research (DZL), Justus-Liebig-University Giessen, Giessen, Germany.
Ralph T SchermulyDepartment of Internal Medicine, Member of the German Center for Lung Research (DZL), Justus-Liebig-University Giessen, Giessen, Germany.
Philip EatonWilliam Harvey Research Institute and.
Rebecca L CharlesWilliam Harvey Research Institute and.ORCID 0000-0003-4115-6135

Funding

Barts Charity G002413Barts Charity G00913British Heart Foundation FS/17/36/32874
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epoxide HydrolasesHypertension, PulmonaryZincAnimalsDisease Models, AnimalFemaleHumansHypoxiaMaleMiceMiddle AgedPulmonary ArteryPulmonary Disease, Chronic ObstructiveVascular RemodelingEpoxide HydrolasesZinccysteinehypoxialung diseasevasoconstriction

Identifiers

PMID40504769
PMCPMC12499926

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.