Evidence mapPaperPMID 40507448Full record

ReviewJournal of clinical medicine2025

Advancements in Spinal Endoscopic Surgery: Comprehensive Techniques and Pathologies Addressed by Full Endoscopy Beyond Lumbar Disc Herniation.

Jad El Choueiri, Francesca Pellicanò, Edoardo Caimi, Francesco Laurelli, Leonardo Di Cosmo, Ali Darwiche Rada, Daniel Cernigoi, Arosh S Perera Molligoda Arachchige, Giorgio Cracchiolo, Donato Creatura and 3 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jad El ChoueiriHumanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.ORCID 0009-0002-6048-891X
Francesca PellicanòHumanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.ORCID 0009-0004-7484-668X
Edoardo CaimiHumanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.ORCID 0000-0002-8591-3903
Francesco LaurelliHumanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.ORCID 0000-0002-6723-8385
Leonardo Di CosmoHumanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.ORCID 0009-0007-7237-633X
Ali Darwiche RadaHumanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.
Daniel CernigoiHumanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.
Arosh S Perera Molligoda ArachchigeHumanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.
Giorgio CracchioloSchool of Medicine and Surgery, University of Milano-Bicocca, 24127 Bergamo, Milan, Italy.ORCID 0009-0007-3049-360X
Donato CreaturaDepartment of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy.ORCID 0009-0000-2696-5685
Ali BaramDepartment of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy.ORCID 0000-0001-6081-5963
Carlo BrembillaDepartment of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy.ORCID 0000-0003-3356-3144
Gabriele CapoDepartment of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy.ORCID 0000-0002-2810-7622

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic spine surgery (ESS) has traditionally been employed for lumbar disc herniation (LDH). Recent innovations in surgical methods and technologies have expanded its range to address other spinal pathologies, providing minimally invasive solutions with potential clinical benefits. Our review aims to summarize the applications, clinical outcomes, and limitations of ESS beyond LDH, focusing on its role in complex spinal conditions such as stenosis, thoracic disc herniation, spinal tumors, synovial cysts, and failed back surgery syndrome. A thorough review of the literature was conducted to assess and summarize the current evidence regarding ESS applications for spinal conditions beyond LDH surgery. Areas of focus included innovations in technology and technique, as well as comparisons with conventional open surgical methods. ESS shows notable potential across different spinal conditions by providing minimally invasive alternatives to traditional open surgery. Its use could be associated with reduced surgical morbidity, shorter recovery times, and improved patient outcomes. In particular, ESS is versatile in addressing both degenerative and neoplastic conditions of the spine. Despite this, challenges such as technical complexity, steep learning curves, and limited indications for certain pathologies remain as barriers to wider adoption. ESS is evolving in spine surgery, extending its utility beyond LDH surgery. While the current evidence largely supports its clinical efficacy, further studies are needed to address the present limitations and optimize its application. Future developments in surgical training and technology will likely enhance its adoption and broaden its clinical indications.

Indexed as

endoscopic spine surgeryFESS—full-endoscopic spine surgeryminimally invasivespine managementUBE—unilateral biportal endoscopy

Identifiers

PMID40507448
PMCPMC12156365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.