Evidence map›Paper›PMID 40507782›Full record

ReviewInternational journal of molecular sciences2025

Ciliary G-Protein Coupled Receptor Signaling in Polycystic Kidney Disease.

Raghad Buqaileh, Lubna A Alshriem, Wissam AbouAlaiwi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. SAR-Guided Scaffold Innovation of Selective VACS medicinal chemistry letters · 2026
    Article
  4. Review
  5. Ciliary-Mediated Mechanotransduction in Skeletal Development and Diseases.Results and problems in cell differentiation · 2026
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raghad BuqailehDepartment of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USA.
Lubna A AlshriemDepartment of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USA.ORCID 0000-0001-5278-5311
Wissam AbouAlaiwiDepartment of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH 43614, USA.ORCID 0000-0002-8226-3108

Funding

Program to Increase Diversity in Cardiovascular Health-Related Research(PRIDE-CVD)R25HL105446 · NHLBI · SUNY DOWNSTATE MEDICAL CENTER · PI Mohamed Boutjdir · 2010 to 2026
$5.9M
Cerebrovascular endothelial cilia in the pathogenesis and therapy of Alzheimer's diseaseR03AG080418 · NIA · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI ABOUALAIWI, WISSAM · 2023 to 2024
$301k
NHLBI NIH HHS R25 HL105446NIA NIH HHS R03 AG080418
6 · The paper itself

Abstract

Polycystic kidney disease (PKD), a ciliopathy caused primarily by mutations in the

Indexed as

CiliaPolycystic Kidney DiseasesReceptors, G-Protein-CoupledSignal TransductionAnimalsHumansTRPP Cation ChannelsReceptors, G-Protein-CoupledTRPP Cation ChannelsADPKDGPCRpolycystic kidney diseasepolycystinprimary cilia

Identifiers

PMID40507782
PMCPMC12154282

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.