Evidence map›Paper›PMID 40508524›Full record

ReviewMaterials (Basel, Switzerland)2025

Unveiling the Potential of Bioactive Glass in Volumetric Muscle Loss Regeneration.

Andreea-Alina Zăvoi, Alexandra Dreancă, Klara Magyari, Lucian Baia, Ciprian Ober, Liviu Oana

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andreea-Alina ZăvoiFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Alexandra DreancăFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Klara MagyariNanostructured Materials and Bio-Nano-Interfaces Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, 400084 Cluj-Napoca, Romania.ORCID 0000-0003-1770-8454
Lucian BaiaNanostructured Materials and Bio-Nano-Interfaces Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, 400084 Cluj-Napoca, Romania.ORCID 0000-0003-3196-4868
Ciprian OberFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0003-3997-725X
Liviu OanaFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.

Funding

Ministry of Research, Innovation and Digitalization PN-III-P2-2.1-PED-2021-2176
6 · The paper itself

Abstract

Injuries characterized by significant loss of skeletal muscle tissue volume, known as volumetric muscle loss (VML), lead to substantial impairment in functional capabilities. Natural repair processes and existing medical interventions fall short of fully restoring function post-VML. Despite progress in the VML field, there is an unsatisfactory success rate, donor site morbidity, and inefficient reconstruction of lost muscle tissue. This leads to persistent strength and functional deficits, impacting the quality of life for VML patients. In recent years, studies have explored the potential of bioactive glasses (BGs) as crucial materials in regenerating tissues beyond the skeletal system. BG, used mainly in bone engineering, can aid muscle repair by releasing ions like calcium and phosphate to stimulate cellular response. However, current BG composites struggle to match the mechanical properties of soft tissues, limiting seamless healing. This review summarizes recent advances in various BG structures studied for skeletal muscle tissue regeneration.

Indexed as

bioactive glassesskeletal muscle regenerationtissue engineeringvolumetric muscle loss

Identifiers

PMID40508524
PMCPMC12156440

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.