ArticleAnimals : an open access journal from MDPI2025
Is Canine Prostate-Specific Esterase a Reliable Marker for Benign Prostatic Hyperplasia Progression in Dogs?
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Grading Canine Benign Prostatic Hyperplasia: A Survey of Veterinary Practice and the Development of a Web-Based Symptom Index.Animals : an open access journal from MDPI · 2026Article
- Ultrasonographic Appearance of Acute Prostatitis and Prostatic Abscesses in Dogs.Animals : an open access journal from MDPI · 2026Article
- Association of Blood Plasma Vascular Endothelial Growth Factor and Testicular Artery Doppler Parameters with Canine Sperm Freezability.Animals : an open access journal from MDPI · 2026Article
- Comprehensive Insight into the Male Dog Reproductive System in Health and Diseases: Developmental, Genetic, and Environmental Factors-Review on Research and Clinical Trials.Veterinary sciences · 2026Review
- Post-Ejaculatory Blood Plasma Canine Prostate-Specific Esterase Concentrations May Predict Total Motility Decline After Sperm Freezing in Dogs.Animals : an open access journal from MDPI · 2026Article
- The urethro-prostatic angle as a practical sonographic index for estimating prostatic size in dogs.Frontiers in veterinary science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Benign prostatic hyperplasia (BPH) is a common condition in intact male dogs, often progressing from subclinical to symptomatic stages with increasing clinical and structural impact. This study evaluated canine prostate-specific esterase (CPSE) as a biomarker for BPH progression, focusing on clinical severity, complexity, and ultrasonographic features. Seventy-one dogs were included: subclinical-BPH (n = 14), clinical-BPH (n = 26), BPH-prostatitis (n = 9), and controls (n = 22). CPSE levels, measured using a canine-specific enzyme-linked immunosorbent assay, were significantly correlated with clinical severity (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.