Assessing Nitrosamine Migration from Drinking Water Contact Materials Using a Validated LLE-GC-MS Method.

Beatriz Antunes, Andreia Videira, Ana Penetra, Vitor V Cardoso, Rui N Carneiro, Cristina M M Almeida

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beatriz AntunesiMed.UL, Faculdade de Farmácia, Universidade de Lisboa, 1649-003 Lisboa, Portugal.

Andreia VideiraDireção de Laboratórios, Empresa Portuguesa das Águas Livres, S.A.-EPAL, 800-003 Lisboa, Portugal.

Ana PenetraDireção de Laboratórios, Empresa Portuguesa das Águas Livres, S.A.-EPAL, 800-003 Lisboa, Portugal.

Vitor V CardosoDireção de Laboratórios, Empresa Portuguesa das Águas Livres, S.A.-EPAL, 800-003 Lisboa, Portugal.ORCID 0000-0001-8144-2000

Rui N CarneiroDireção de Laboratórios, Empresa Portuguesa das Águas Livres, S.A.-EPAL, 800-003 Lisboa, Portugal.

Cristina M M AlmeidaiMed.UL, Faculdade de Farmácia, Universidade de Lisboa, 1649-003 Lisboa, Portugal.ORCID 0000-0002-6872-9127

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrosamines (NAs) are toxic compounds associated with disinfection processes. Human exposure can occur through the hydraulic hoses and seals that are in contact with drinking water. This study develops and validates a chromatographic method to quantify 11 NAs in water leachates from four organic materials. The method is based on liquid-liquid extraction (LLE) followed by gas chromatography coupled with mass spectrometry (GC-MS). The method was validated by the application of several statistical tests, namely, linearity/working range, precision, trueness, and recovery tests. The GC-MS method showed a good linear range for all NAs with coefficients of determination (r

Indexed as

Drinking WaterGas Chromatography-Mass SpectrometryLiquid-Liquid ExtractionNitrosaminesWater Pollutants, ChemicalReproducibility of ResultsDrinking WaterNitrosaminesWater Pollutants, ChemicalGC-MSLLEmaterialsmigration assaysnitrosamineswater

Identifiers

PMID40509288

DOI10.3390/molecules30112403

PMCPMC12156258

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.