Evidence map›Paper›PMID 40509407›Full record

ReviewFoods (Basel, Switzerland)2025

Research Progress on Probiotics in Alleviating Cow's Milk Allergy: A Review.

Yangze Guo, Jiali Chen, Yezhi Qu, Xilin Wu, Shengyi Zhang, Jiale Wang, Xiqing Yue, Zhenmin Liu, Aijun Xie, Mohan Li

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yangze GuoCollege of Food Science, Shenyang Agricultural University, Shenyang 110866, China.
Jiali ChenCollege of Food Science, Shenyang Agricultural University, Shenyang 110866, China.
Yezhi QuState Key Laboratory of Dairy Biotechnology, Shanghai Engineering Research Center of Dairy Biotechnology, Shanghai 200436, China.
Xilin WuCollege of Food Science, Shenyang Agricultural University, Shenyang 110866, China.
Shengyi ZhangCollege of Food Science, Shenyang Agricultural University, Shenyang 110866, China.
Jiale WangCollege of Food Science, Shenyang Agricultural University, Shenyang 110866, China.
Xiqing YueCollege of Food Science, Shenyang Agricultural University, Shenyang 110866, China.ORCID 0000-0001-5558-1461
Zhenmin LiuState Key Laboratory of Dairy Biotechnology, Shanghai Engineering Research Center of Dairy Biotechnology, Shanghai 200436, China.ORCID 0000-0003-3777-087X
Aijun XieDepartment of Biological Systems Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-5993-8787
Mohan LiState Key Laboratory of Dairy Biotechnology, Shanghai Engineering Research Center of Dairy Biotechnology, Shanghai 200436, China.ORCID 0000-0002-0901-4615

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cow's milk allergy (CMA) is one of the most common food allergies in infancy, capable of triggering severe allergic reactions. Alterations in gut microbial composition and function may be closely related to the development of CMA. Probiotics, as a means to modulate the gut microbial composition, demonstrate potential in controlling allergic reactions by enhancing gut barrier functions, promoting immune responses in the intestinal mucosa, and degrading potential allergens. Therefore, probiotics are increasingly considered a promising strategy for managing CMA. This review summarizes the major allergens in cow's milk, their mechanisms of allergenicity, and the role and mechanisms of probiotics in alleviating CMA. It aims to provide a deeper understanding and fresh perspectives to support the use of probiotics as an effective approach for the prevention and treatment of CMA, encouraging broader clinical application and research.

Indexed as

cow’s milk allergygut microbiotaoral toleranceprobiotics

Identifiers

PMID40509407
PMCPMC12155488

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.