Evidence map›Paper›PMID 40511049›Full record

ArticleJournal of pharmacy & bioallied sciences2025

Seed Cycling and Hormonal Balance: A Case Study of Successful Fertility Intervention in Polycystic Ovarian Syndrome.

Puja Dhamija, Akash More, Namrata Choudhary, Tejaswini Wadhe, Juhi Barai, Devanshi Shah

Abstract readCase Reports
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Puja DhamijaClinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.
Akash MoreAssociate Professor, Chief Embryologist, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research Wardha, Maharashtra, India.
Namrata ChoudharySchool of Allied Health Science, Datta Meghe Institute of Higher Education and Research (DU), Sawangi (Meghe), Wardha, Maharashtra, India.
Tejaswini WadheClinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.
Juhi BaraiClinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.
Devanshi ShahClinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case study discusses the treatment of primary infertility in a 29-year-old female with a case of polycystic ovarian syndrome (PCOS) who presented to the Infertility Clinic at Wardha, Maharashtra, with a 2-year history of failed conception. The female patient complains about irregular menstrual cycles, mild acne, hair thinning weight gain, and hormonal imbalances characterized by high luteinizing hormone (LH), low levels of follicle-stimulating hormone (FSH), and a raised LH: FSH ratio. Following the initial evaluations, they were put on a comprehensive fertility treatment plan that incorporated Myo-inositol and folic acid supplementation, and seed cycling as a dietary intervention. The seed cycling protocol involved the consumption of ground flaxseeds and pumpkin seeds during the follicular phase and sunflower and sesame seeds during the luteal phase to balance estrogen and progesterone, respectively. After 6 months, the patient experienced notable improvements such as regular menstrual cycles, a reduction in body mass index ranges from 29 to 24 kg/m², normalized hormone levels, and the male partner's semen analysis representing results within normal limits. The couple moved forward with intracytoplasmic sperm injection, which led to the development of high-quality embryos and a confirmed clinical pregnancy outcome. This case highlights the effectiveness of integrating pharmacological treatment with seed cycling to improve fertility outcomes in patients with PCOS.

Indexed as

Dietary therapyendocrine disorderlifestyle modificationsnonpharmacological treatmentPCOSprimary infertilityseed cycling

Identifiers

PMID40511049
PMCPMC12156535

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.