Evidence map›Paper›PMID 40512126›Full record

ArticleG3 (Bethesda, Md.)2025

Genome report: whole-genome assembly of the relapsing fever tick Ornithodoros turicata Dugès (Acari: Argasidae).

Mackenzie Tietjen, Amanda R Stahlke, David Luecke, Perot Saelao, Sheina B Sim, Scott M Geib, Brian E Scheffler, Anna K Childers, Alexander R Kneubehl, Pete D Teel and 1 more

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mackenzie TietjenUSDA Agricultural Research Service, Livestock Arthropod Pest Research Unit, 2700 Fredericksburg Road, Kerrville, TX 78028, USA.ORCID 0000-0001-7854-6845
Amanda R StahlkeDepartment of Biology, Colorado Mesa University, 1100 North Ave, Grand Junction, CO 81501, USA.ORCID 0000-0001-5724-598X
David LueckeUSDA Agricultural Research Service, Veterinary Pest Genetics Research Unit, 2700 Fredericksburg Road, Kerrville, TX 78028, USA.ORCID 0000-0001-5309-9153
Perot SaelaoUSDA Agricultural Research Service, Veterinary Pest Genetics Research Unit, 2700 Fredericksburg Road, Kerrville, TX 78028, USA.ORCID 0000-0003-1171-9187
Sheina B SimUSDA Agricultural Research Service, US Pacific Basin Agricultural Research Center, Tropical Crop and Commodity Protection Research Unit, 64 Nowelo Street, Hilo, HI 96720, USA.ORCID 0000-0003-0914-6914
Scott M GeibUSDA Agricultural Research Service, US Pacific Basin Agricultural Research Center, Tropical Crop and Commodity Protection Research Unit, 64 Nowelo Street, Hilo, HI 96720, USA.
Brian E SchefflerUSDA Agricultural Research Service, Jamie Whitten Delta States Research Center, Genomics and Bioinformatics Research Unit, 141 Experiment Station Road, Stoneville, MS 38776, USA.
Anna K ChildersUSDA Agricultural Research Service, Beltsville Agricultural Research Center, Bee Research Laboratory, 10300 Baltimore Avenue, Beltsville, MD 20705, USA.ORCID 0000-0002-0747-8539
Alexander R KneubehlDepartment of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Pete D TeelDepartment of Entomology, Texas A&M AgriLife Research, College Station, TX 77843, USA.
Job E LopezDepartment of Pediatrics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

Funding

Research Training in Infections and ImmunityT32AI055413 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GIORDANO, THOMAS P, MYSOREKAR, INDIRA U · 2003 to 2024
$3.2M
NIAID NIH HHS T32 AI055413U.S. Department of Agriculture, Agricultural Research Service 0500-00093-001-00-D
6 · The paper itself

Abstract

The soft tick family Argasidae contains vectors of medical and veterinary importance, but few molecular resources are available compared to hard ticks (Ixodidae). One example is Ornithodoros turicata, a recognized vector of Borrelia turicatae, causal agent of human relapsing fever, and a putative vector of African swine fever virus. To address the current lack of molecular resources for the Argasidae, we generated a chromosome-level genome assembly for O. turicata using PacBio sequencing in conjunction with an Illumina Hi-C library. The resulting reference genome has a total of 1.1 Gb in length and was assembled into 10 chromosomes and 368 unplaced scaffolds, an N50 of 2.7 Mb, and a QV score of 43.58. The orthology analysis indicated high-quality with a 97.8% BUSCO completeness score and 36,149 annotated genes. 33% of the genome was identified as repeats and masked. The generation of the first soft tick reference genome establishes a basis for future studies to utilize genomic tools to support vector-borne disease management.

Indexed as

GenomeOrnithodorosAnimalsBorreliaGenomicsHigh-Throughput Nucleotide SequencingMolecular Sequence AnnotationRelapsing FeverWhole Genome Sequencinggenome assemblyreference genomerelapsing fever ticksoft tick

Identifiers

PMID40512126
PMCPMC12239604

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.