Evidence map›Paper›PMID 40512903›Full record

ArticleOptics letters2025

Doppler OCT verifies pulsation-induced anisotropic vessel lumen dynamics in the human retina.

Tobiloba Adejumo, Taeyoon Son, Guangying Ma, Mojtaba Rahimi, Albert Dadzie, Jie Ding, Xincheng Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Optics letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tobiloba Adejumo
Taeyoon Son
Guangying Ma
Mojtaba Rahimi
Albert Dadzie
Jie Ding
Xincheng Yao

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · UNIVERSITY OF ILLINOIS AT CHICAGO · 1985 to 2025
$3.9M
Differential artery-vein analysis in OCT angiography for objective classification of diabetic retinopathyR01EY030842 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jennifer Irene Lim, XINCHENG YAO · 2023 to 2023
$363k
Functional tomography of neurovascular coupling interactions in healthy and diseased retinasR01EY030101 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI XINCHENG YAO · 2022 to 2022
$304k
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY023522NEI NIH HHS R01 EY029673NEI NIH HHS R01 EY030101NEI NIH HHS R01 EY030842NEI NIH HHS R44 EY028786
6 · The paper itself

Abstract

This study verifies anisotropic vessel pulsatility in human retinas. Doppler optical coherence tomography (OCT) was utilized for dynamic monitoring of peripapillary vessel lumen dynamics. Quantitative analysis consistently revealed larger axial compared to lateral lumen changes, with an axial-to-lateral pulsation change ratio of 1.26 ± 0.08. These findings highlight the anisotropic biomechanical properties of retinal tissues, which contribute to direction-dependent vascular dynamics. Quantitative assessment of anisotropic vascular biomechanics offers promising insights for improving the detection of vascular alterations associated with ocular conditions.

Indexed as

RetinaRetinal VesselsTomography, Optical CoherenceAnisotropyHumans

Identifiers

PMID40512903
PMCPMC12374261

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.