Evidence map›Paper›PMID 40513566›Full record

ReviewStem cell reports2025

Promoting the adoption of best practices and standards to enhance quality and reproducibility of stem cell research.

Lucia Selfa Aspiroz, Milena Mennecozzi, Laura Batlle, Barbara Corneo, Lyn Healy, Mark Kotter, Andreas Kurtz, Tenneille E Ludwig, Christine Mummery, Martin Pera and 3 more

Abstract readReview
In one paragraph

Review in Stem cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Modeling pediatric brain tumors with human stem cells.Frontiers in cellular neuroscience · 2026
    Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lucia Selfa AspirozEuropean Commission, Joint Research Centre (JRC), Ispra, Italy. Electronic address: idoia-lucia.selfa-aspiroz@ec.europa.eu.
Milena MennecozziEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Laura BatlleTissue Engineering Unit, Center for Genomic Regulation (CRG), Barcelona, Spain.
Barbara CorneoStem Cell Core, Columbia University, New York, NY, USA.
Lyn HealyHuman Embryo and Stem Cell Unit, Human Biology Facility, The Francis Crick Institute, London, UK.
Mark KotterUniversity of Cambridge and bit.bio Ltd, Cambridge, UK.
Andreas KurtzBerlin Institute of Health at Charite, Center for Regenerative Therapies, Berlin, Germany.
Tenneille E LudwigWiCell Research Institute, Madison, WI, USA; Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, WI, USA.
Christine MummeryDepartment of Anatomy and Embryology, Institute of Human Organ and Disease Model Technologies (hDMT), Dept of Anatomy and Embryology, Leiden University Medical Center, Leiden, the Netherlands.
Martin PeraThe Jackson Laboratory, Bar Harbor, ME USA.
Glyn N StaceyInternational Stem Cell Biobanking Initiative, Barley, Hertfordshire, UK; National Stem Cell Resource Centre, Institute of Zoology, Chinese Academy of Sciences, Beijing, China; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.
Carlos A TristanNational Center for Advancing Translational Sciences (NCATS), Stem Cell Translation Laboratory (SCTL), National Institutes of Health (NIH), Rockville, MD, USA.
Maurice WhelanEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancing the use of human stem cell-based models on preclinical and regulatory testing fields requires the performance of rigorous and reproducible research. Quality standards and reporting best practices should be promoted to ensure the reliability and translatability of stem cell models and results. Strategies to increase awareness and implementation of best practices and standards will require training initiatives and collaboration across relevant stakeholders. Overall, improving the quality and reproducibility of stem cell-based models and methods through best practices and standards will accelerate their adoption in industrial and regulatory contexts and ultimately drive the development of effective therapies and safer chemicals.

Indexed as

Stem Cell ResearchStem CellsHumansQuality ControlReproducibility of Resultsadoptionbest practiceshiPSCimplementationqualityreproducibilitystakeholdersstandardsstem cell

Identifiers

PMID40513566
PMCPMC12277813

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.