Evidence map›Paper›PMID 40513952›Full record

Trial reportThe American journal of clinical nutrition2025

A digital behavioral intervention to reduce sugar-sweetened beverage consumption: a randomized, controlled trial.

Jamie M Zoellner, Wen You, Kathleen Porter, Annie L Reid, Donna-Jean P Brock, Theresa Markwalter, Christina Frederick, Deborah F Tate, Lee Ritterband

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05030753 (iSIPsmarter), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05030753 nacompletednot on this map

iSIPsmarter: An RCT to Evaluate the Efficacy, Reach, and Engagement of a Technology-based Behavioral and Health Literacy Intervention to Reduce Sugary Beverages Among Rural Appalachian Adults

TypeinterventionalSponsorUniversity of VirginiaRan2021 to 2024Enrolled249ConditionsDiet Habit, Sugar-Sweetened BeveragesArmsiSIPsmarter, Patient Education (PE)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jamie M ZoellnerDepartment of Public Health Sciences, UVA Cancer Center Research and Outreach Office, University of Virginia, Christiansburg, VA, United States. Electronic address: jz9q@virginia.edu.
Wen YouDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, United States.
Kathleen PorterDepartment of Public Health Sciences, UVA Cancer Center Research and Outreach Office, University of Virginia, Christiansburg, VA, United States.
Annie L ReidDepartment of Public Health Sciences, UVA Cancer Center Research and Outreach Office, University of Virginia, Christiansburg, VA, United States.
Donna-Jean P BrockDepartment of Public Health Sciences, UVA Cancer Center Research and Outreach Office, University of Virginia, Christiansburg, VA, United States.
Theresa MarkwalterDepartment of Public Health Sciences, UVA Cancer Center Research and Outreach Office, University of Virginia, Christiansburg, VA, United States.
Christina FrederickDepartment of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, United States.
Deborah F TateDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, United States.
Lee RitterbandDepartment of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, United States.

Funding

Optimizing iSIPsmarter: A Factorial Trial to Enhance Engagement and Effectiveness on Sugary Beverages and Weight among rural Appalachian adultsR01MD015033 · NIMHD · UNIVERSITY OF VIRGINIA · PI Lee M Ritterband, Jamie Zoellner · 2020 to 2026
$4.2M
NIMHD NIH HHS R01 MD015033
6 · The paper itself

Abstract

backgroundReducing sugar-sweetened beverages (SSB) is a worldwide public health priority. There are United States regions with notable SSB consumption pattern disparities, including Appalachia.

objectivesWe aimed to measure the efficacy of a digital behavioral intervention in reducing SSB consumption. Weight and quality of life (QOL) were also explored.

methodsIn this 2-group randomized-controlled trial targeting adults living in Appalachia, participants were randomly assigned to either an interactive, structured, digital intervention comprised of 6 cores, behavioral tracking, and personalized action planning, or a static patient education website. At baseline and at 9-wk and 6-mo postintervention, validated measures were used to assess SSB intake and QOL. Weight was captured using cellular-enabled scales.

resultsParticipants (n = 249) were 88% Caucasian, 83% female, 52% with income <$55,000/y, 86% from more rural counties, and 84% with overweight or obesity. In the digital intervention group, the mean core completion was 5.2 [standard deviation (SD) = 1.6] of 6 cores, and participants tracked a mean of 76% (SD = 29%) of daily SSB diaries and 57% (SD = 31%) of daily weights. At 9-wk, digital intervention participants [-896.1 mL/d; 95% confidence interval (CI): -1043.9, -748.2 mL/d] consumed 289.8 (95% CI: -493.9, -88.7) less SSB mL/d than comparison participants (-606.3 mL/d; 95% CI: -745.3, -467.9 mL/d) [effect size (ES) = 0.37; P = 0.005]. The 6-mo assessment was similar, with digital intervention participants consuming an average of 280.9 (95% CI: -490.9, -68.0) less SSB mL/d than comparison participants (ES = 0.35; P = 0.009). There was no significant between-condition QOL effects, yet QOL improved within both conditions (P < 0.001). At 6-mo, body weight was significantly reduced for digital intervention relative to comparison participants (ES = 0.23; P = 0.046).

conclusionsA digital behavioral intervention was efficacious in reducing SSB consumption among Appalachian adults and yielded high engagement and retention rates. This intervention should be evaluated in other populations with excessive SSB consumption. This trial was registered at clincialtrials.gov as NCT05030753.

Indexed as

Behavior TherapyFeeding BehaviorSugar-Sweetened BeveragesAdultAgedAppalachian RegionFemaleHumansMaleMiddle AgedObesityOverweightQuality of Lifebehavioral researchdigital technologyeHealthinternet-based interventionrural populationsugar-sweetened beverages

Identifiers

PMID40513952
PMCPMC12405787

What Socratic holds

Textmetadata
LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.