ArticleArchives of public health = Archives belges de sante publique2025
Cumulative handgrip strength and longitudinal changes in cognitive function and daily functioning among people aged 50 years and older: evidence from two longitudinal cohort studies.
Article in Archives of public health = Archives belges de sante publique, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk.SSM - population health · 2026Article
- Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk.medRxiv : the preprint server for health sciences · 2026Article
- Preserved muscle function as a protective factor against cognitive decline: Longitudinal results from the FINGER study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Observational
- Associations Between Physical Activity Frequency, Handgrip Strength, and Limitations in Activities of Daily Living in Middle-Aged and Older Adults with Widespread Pain: A Cross-Sectional Study Using Data from the SHARE Project.Geriatrics (Basel, Switzerland) · 2025Article
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Authors and funding
10 authors.
Funding
Abstract
background and purposeOur study assesses the association between cumulative handgrip strength and longitudinal changes in cognitive function and daily functioning.
methodsTwo comparative cohort studies were used, including the English Longitudinal Study of Ageing (ELSA) and the Survey of Health, Ageing and Retirement in Europe (SHARE). Cumulative handgrip strength was calculated using three repeated measurements of handgrip strength. Linear mixed regression models evaluated the association between cumulative handgrip strength and longitudinal changes in cognitive function and daily functioning. Cox regression models were performed to determine the association between cumulative handgrip strength and the risk of cognitive and functional impairment.
resultsIndividuals with lower levels of cumulative handgrip strength had lower global cognition (β: -0.244; 95% CI: -0.317, -0.170 for ELSA and -0.359; -0.406, -0.311 for SHARE) and experienced a faster decline in cognitive function over time (-0.025; -0.037, -0.013 for ELSA, and -0.019; -0.026, -0.013 in SHARE). We found lower levels of cumulative handgrip strength were associated with lower daily functioning (β: 0.267; 95% CI: 0.161, 0.374 for ELSA and 0.153; 0.079, 0.227 for SHARE), and a faster decline in daily functioning over time (0.105; 0.081, 0.129 for ELSA and 0.217; 0.195, 0.238 for SHARE). Furthermore, lower levels of cumulative handgrip strength were related to a higher risk of cognitive and functional impairment.
conclusionsOur study suggested that lower levels of cumulative handgrip strength was related to an accelerated decline in cognitive function and daily functioning. Persistently strengthening muscle strength should be emphasized in preventing neurodegenerative disorders and disabilities.
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