Evidence map›Paper›PMID 40515749›Full record

ReviewThe Journal of investigative dermatology2025

Cutaneous Hormone Sampling and Analysis for Dermatologic Research.

Camille I Sturges, Shivani Jain, Mauricio Velasquez, Hanna Gedamu, Jessica Komarovsky, Jeffrey McDonald, Tamia Harris-Tryon

Abstract readReview
In one paragraph

Review in The Journal of investigative dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Camille I SturgesDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Shivani JainDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Mauricio VelasquezCenter for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Hanna GedamuDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jessica KomarovskyDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jeffrey McDonaldCenter for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Tamia Harris-TryonDepartment of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. Electronic address: tamia.harris-tryon@utsouthwestern.edu.

Funding

Androgens modulate Staphylococcus aureus signaling and pathogenesisR01AI187273 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Tamia Alisha Harris-Tryon · 2025 to 2026
$1.3M
The Function of Small Proline Rich Proteins in Cutaneous Host DefenseK08AR076459 · NIAMS · UT SOUTHWESTERN MEDICAL CENTER · PI HARRIS-TRYON, TAMIA ALISHA · 2020 to 2024
$798k
NIAID NIH HHS R01 AI187273NIAMS NIH HHS K08 AR076459
6 · The paper itself

Abstract

The skin can generate hormones through de novo steroid hormone synthesis. These hormones have been shown to play a significant role in inflammatory skin conditions through the regulation of skin immunity, sebum production, and skin barrier function. Although there is growing interest in understanding the composition and function of skin hormones throughout the human lifespan and in various pathologies, there remains a need to standardize sampling and quantification methods. In this article, we discuss an emerging noninvasive approach in skin hormone quantification through adhesive sebum collection tape followed by analysis through mass spectrometry or hormone-specific immunoassays. This approach is highly adaptable, allowing for repetitive sampling over time and across diverse study populations.

Indexed as

DermatologyHormonesSebumSkinSpecimen HandlingHumansImmunoassayMass SpectrometryHormonesAcneAtopic dermatitisHidradenitis suppurativaHormoneMethods and Techniques in Skin ResearchSteroid

Identifiers

PMID40515749
PMCPMC12302376

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.