Evidence mapPaperPMID 40517148Full record

ArticleNPJ digital medicine2025

A scoping review and evidence gap analysis of clinical AI fairness.

Mingxuan Liu, Yilin Ning, Salinelat Teixayavong, Xiaoxuan Liu, Mayli Mertens, Yuqing Shang, Xin Li, Di Miao, Jingchi Liao, Jie Xu and 10 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Ethical Considerations in Personal Health Large Language Models.Journal of medical Internet research · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Then and Now: What We Have Learned From the WHI.The Journal of clinical endocrinology and metabolism · 2026
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Mingxuan Liu *Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0002-4274-9613
Yilin Ning *Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0002-6758-4472
Salinelat TeixayavongCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Xiaoxuan LiuCollege of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Mayli MertensAntwerp Center on Responsible AI, Department of Philosophy, University of Antwerp, Antwerp, Belgium.ORCID http://orcid.org/0000-0002-9883-9167
Yuqing ShangCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Xin LiCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Di MiaoCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0009-0008-5381-9198
Jingchi LiaoCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Jie XuDepartment of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0001-5291-5198
Daniel Shu Wei TingCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Lionel Tim-Ee ChengDepartment of Diagnostic Radiology, Singapore General Hospital, Singapore, Singapore.ORCID http://orcid.org/0000-0002-1068-7868
Jasmine Chiat Ling OngDepartment of Pharmacy, Singapore General Hospital, Singapore, Singapore.ORCID http://orcid.org/0000-0001-6916-5960
Zhen Ling TeoSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.ORCID http://orcid.org/0000-0003-3443-8601
Ting Fang TanSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.ORCID http://orcid.org/0000-0001-7348-9749
Narrendar RaviChandranSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.ORCID http://orcid.org/0000-0001-7365-0053
Fei WangDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-9459-9461
Leo Anthony CeliLaboratory for Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-6712-6626
Marcus Eng Hock OngProgramme in Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.
Nan LiuCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore. liu.nan@duke-nus.edu.sg.ORCID http://orcid.org/0000-0003-3610-4883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ethical integration of artificial intelligence (AI) in healthcare necessitates addressing fairness. AI fairness involves mitigating biases in AI and leveraging AI to promote equity. Despite advancements, significant disconnects persist between technical solutions and clinical applications. Through evidence gap analysis, this review systematically pinpoints the gaps at the intersection of healthcare contexts-including medical fields, healthcare datasets, and bias-relevant attributes (e.g., gender/sex)-and AI fairness techniques for bias detection, evaluation, and mitigation. We highlight the scarcity of AI fairness research in medical domains, the narrow focus on bias-relevant attributes, the dominance of group fairness centering on model performance equality, and the limited integration of clinician-in-the-loop to improve AI fairness. To bridge the gaps, we propose actionable strategies for future research to accelerate the development of AI fairness in healthcare, ultimately advancing equitable healthcare delivery.

Identifiers

PMID40517148
PMCPMC12167363

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.