Evidence map›Paper›PMID 40517183›Full record

ArticleInternational journal of colorectal disease2025

Preoperative CT-derived sarcopenia as a predictor of postoperative complications in patients undergoing laparoscopic radical resection for non-metastatic colorectal cancer: a retrospective study.

Shuyan Su, Zejia Lin, Zelong Cai, Lipeng Huang, Yubin Xiao, Fangjie Yang, Xiujie Huang, Yikai Chen, Zhuoqun Zheng, Xinxin Li and 1 more

Abstract read
In one paragraph

Article in International journal of colorectal disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shuyan Su *Department of Radiology, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Zejia Lin *Department of Gastrointestinal Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Zelong Cai *Department of Radiology, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Lipeng HuangDepartment of Radiology, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Yubin XiaoDepartment of Radiology, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Fangjie YangDepartment of Gastrointestinal Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Xiujie HuangDepartment of Gastrointestinal Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Yikai ChenDepartment of Gastrointestinal Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Zhuoqun ZhengDepartment of Gastrointestinal Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China.
Xinxin LiDepartment of Gastrointestinal Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China. xxli2023@163.com.
Ruibin HuangDepartment of Radiology, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, Guangdong, China. rbhuang1@stu.edu.cn.

Funding

2023 Guangdong Province Medical Research Fund Projects A2023264Basic and Applied Basic Research Foundation of Guangdong Province 2024A151522098
6 · The paper itself

Abstract

purposeSarcopenia is increasingly recognized as a risk factor for postoperative complications in gastrointestinal cancer surgery. This study aimed to assess the association between sarcopenia and postoperative complications following laparoscopic radical resection of non-metastatic colorectal cancer (CRC).

methodsIn this retrospective study, 387 non-metastatic CRC patients undergoing laparoscopic radical resection were categorized into a sarcopenic group and a non-sarcopenic group based on preoperative skeletal muscle index (SMI, cm

resultsSarcopenia was present in 156 (40.31%) patients. The incidence of postoperative complications was 32.3%, with a serious complication (Clavien-Dindo III-V) rate of 12.1%. Compared with non-sarcopenic patients, sarcopenic patients had significantly higher incidences of total complications (P < 0.001) and severe complications (P = 0.026). Multivariable analysis identified sarcopenia as an independent risk factor for total postoperative complications (OR = 3.42, 95%CI 1.85-6.31). Further analysis of specific types of postoperative complications revealed that anastomotic leakage (P = 0.001), surgical site infection (P = 0.002), and surgical site adverse events (P = 0.001) rates were higher in sarcopenic patients. In multivariable analysis, sarcopenia was independently associated with anastomotic leakage (OR = 3.36, 95%CI = 1.12-10.12) and surgical site adverse events (OR = 3.02, 95%CI = 1.55-5.90).

conclusionsPreoperative CT-derived sarcopenia can predict postoperative complications in patients with non-metastatic CRC undergoing laparoscopic radical resection, particularly anastomotic leakage and surgical site adverse events.

Indexed as

Colorectal NeoplasmsLaparoscopyPostoperative ComplicationsSarcopeniaTomography, X-Ray ComputedAgedFemaleHumansMaleMiddle AgedMultivariate AnalysisPreoperative PeriodRetrospective StudiesRisk FactorsColorectal cancerComputed tomographyPostoperative complicationsSarcopenia

Identifiers

PMID40517183
PMCPMC12167240

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.