Evidence map›Paper›PMID 40518705›Full record

ArticleEuropean stroke journal2025

Sex differences in outcomes after endovascular therapy with prior antiplatelet use: A study from the EVA-TRISP registry.

Roberta Noseda, Federico Rea, Giovanni Bianco, Elias Auer, Mirjam R Heldner, Eike I Piechowiak, Tomas Dobrocky, Patrik Michel, Susanne Wegener, Hakim Baazaoui and 23 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European stroke journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Roberta NosedaDivision of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano, Switzerland.ORCID 0000-0002-4946-7926
Federico ReaDepartment of Statistics and Quantitative Methods, Unit of Biostatistics, Epidemiology and Public Health, University of Milano-Bicocca, Milan, Italy.ORCID 0000-0001-7988-5101
Giovanni BiancoNeurocenter of Southern Switzerland, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Elias AuerDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Mirjam R HeldnerDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Eike I PiechowiakInstitute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Tomas DobrockyInstitute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Patrik MichelStroke Center, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Susanne WegenerDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.ORCID 0000-0003-4369-7023
Hakim BaazaouiDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Philipp BaumgartnerDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Sami CurtzeDepartment of Neurology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Nicolas Martinez-MajanderDepartment of Neurology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0001-8489-7051
Miranda NybondasDepartment of Neurology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0009-0001-2030-7283
Andrea ZiniDepartment of Neurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Maggiore Hospital, Bologna, Italy.
Stefano ForlivesiDepartment of Neurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Maggiore Hospital, Bologna, Italy.
Matteo PaolucciDepartment of Neurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Maggiore Hospital, Bologna, Italy.ORCID 0000-0002-5347-378X
Gian Marco De MarchisDepartment of Neurology and Stroke Center, University Teaching and Research Hospital, St. Gallen, Switzerland.
Tolga DittrichDepartment of Neurology and Stroke Center, University Teaching and Research Hospital, St. Gallen, Switzerland.
Paul J NederkoornDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Nabila WaliDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0009-0000-5410-7805
Mira KatanStroke Center and Department of Neurology, University Hospital Basel and University of Basel, Basel, Switzerland.
Stefan EngelterStroke Center and Department of Neurology, University Hospital Basel and University of Basel, Basel, Switzerland.
Henrik GensickeStroke Center and Department of Neurology, University Hospital Basel and University of Basel, Basel, Switzerland.
Simon TrüsselStroke Center and Department of Neurology, University Hospital Basel and University of Basel, Basel, Switzerland.
Alessandro PezziniDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Mauro MagoniStroke Unit, ASST Spedali Civili, «Spedali Civili» Hospital, Brescia, Italy.
João Pedro MartoDepartment of Neurology, Hospital de Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.ORCID 0000-0003-2277-5950
Maria Brás MonteiroDepartment of Neurology, Hospital de Egas Moniz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Ronen R LekerDepartment of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Tamer JubehDepartment of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Visnja PadjenNeurology Clinic, University Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.ORCID 0000-0002-6126-8305
Carlo W CeredaNeurocenter of Southern Switzerland, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study assessed sex differences in outcomes after mechanical thrombectomy (MT) with prior antiplatelet use using the EVA-TRISP multinational registry. PATIENTS AND

methodsA cohort of consecutive patients (2015-2023) treated with MT was analysed by sex and prior antiplatelet use in multivariable logistic regression models. Primary outcomes were in-hospital symptomatic intracranial haemorrhage (sICH) and the 3-month modified Rankin Scale (mRS) score.

resultsAmong 7472 patients (47.9% females, older than males: 77 vs 72 years, DISCUSSION AND

conclusionsThis study showed that there is no apparent interaction between patient sex and prior use of antiplatelets in relation to safety and functional outcomes of MT. Therefore, there is no reason to support a different decision-making approach by practicing physicians regarding MT in females and males previously taking antiplatelets.

Indexed as

Endovascular ProceduresIntracranial HemorrhagesIschemic StrokePlatelet Aggregation InhibitorsThrombectomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedRegistriesSex FactorsTreatment OutcomePlatelet Aggregation InhibitorsAcute ischaemic strokeantiplateletsfunctional outcomeintracranial haemorrhagemechanical thrombectomysex differences

Identifiers

PMID40518705
PMCPMC12170539

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.