ArticleSage open pathology
Aspergillosis Osteomyelitis of the Mandible: A Case Report and Literature Review.
Article in Sage open pathology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspergillosis is an uncommon fungal infection caused by Aspergillus species, predominantly affecting immunocompromised individuals. While pulmonary involvement is common, extrapulmonary manifestations such as osteomyelitis are uncommon. Aspergillus osteomyelitis of the mandible is an exceptionally rare and life-threatening condition, posing significant diagnostic and therapeutic challenges. We present the case of a 13-year-old immunocompromised patient diagnosed with this condition. The patient presented with persistent jaw pain, swelling, and radiographic evidence of extensive bone destruction. Diagnosis was confirmed through fungal cultures and histopathological examination, which identified Aspergillus species. The patient underwent surgical debridement and prolonged antifungal therapy, leading to clinical improvement. Aspergillus osteomyelitis of the mandible is exceedingly rare, with only a few cases reported in the literature. Early diagnosis is crucial to prevent further bone destruction and associated complications. This case underscores the importance of considering fungal infections in the differential diagnosis of osteomyelitis, particularly in at-risk populations. It also emphasizes the potential role of antifungal prophylaxis in reducing the severity of invasive fungal infections when they occur. Managing this condition presents significant challenges, including the need for aggressive antifungal therapy and the risk of recurrence.
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