Evidence map›Paper›PMID 40519418›Full record

ArticleCureus2025

Comparison of Platelet-Rich Plasma Properties Used in Athletic Musculoskeletal Conditions: A Clinical Practice Report.

António Pais Neto, Tiago B Cunha, Nuno Pereira, Miguel Reis E Silva

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

António Pais NetoPhysical Medicine and Rehabilitation, Centro de Medicina de Reabilitação de Alcoitão, Cascais, PRT.
Tiago B CunhaPhysical Medicine and Rehabilitation, Centro de Medicina de Reabilitação de Alcoitão, Cascais, PRT.
Nuno PereiraPhysical Medicine and Rehabilitation, Centro de Medicina de Reabilitação de Alcoitão, Cascais, PRT.
Miguel Reis E SilvaPhysical Medicine and Rehabilitation, Health and Performance, Sport Lisboa e Benfica, Lisboa, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluates the properties of platelet-rich plasma (PRP) preparations used by a professional sports club's medical department for treating musculoskeletal conditions in athletes. PRP samples were prepared using 20 ml and 50 ml Hy-tissue® PRP Kits (Fidia Farmaceutici S.p.A., Abano Terme, Italy) from 13 total blood samples. They were analyzed to assess platelet (PLT), leukocyte, and red blood cell concentrations. Results showed both kits effectively concentrated PLT with an average enrichment factor of 2.9×, though the 50 ml kit produced higher total PLT counts (4.7 Bl) than the 20 ml kit (1.7 Bl). White and red blood cell levels were significantly reduced, indicating high PRP purity. DEPA (dose of injected PLT, efficiency of production, purity of the PRP, activation of the PRP) classification revealed a superior quality score, from A to D in the three prior parameters, for the 50 ml kit (BCA vs. CCA). Despite acceptable PLT concentration, the efficiency of PLT recovery was low across both kits. The findings underscore the importance of evaluating PRP characteristics to optimize therapeutic outcomes and highlight the need for protocol refinement to enhance preparation efficiency. These results advocate for standardized reporting and classification to support evidence-based application of PRP in sports medicine.

Indexed as

athletesmusculoskeletal injuriesplatelet concentrationplatelet-rich plasma (prp)sports-related injuries

Identifiers

PMID40519418
PMCPMC12163841

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.