Evidence mapPaperPMID 40519477Full record

ArticleCureus2025

Delayed Postanoxic Encephalopathy Following Acute Carbon Monoxide Poisoning: A Case Report and Literature Review.

Mina Aallam, Nada Nfaoui, Yasmina Zakaria, Mohamed Chraa, Nissrine Louhab

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In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mina AallamNeurology, Mohammed VI University Hospital Center, Marrakesh, MAR.
Nada NfaouiNeurology, Mohammed VI University Hospital Center, Marrakesh, MAR.
Yasmina ZakariaNeurology, Mohammed VI University Hospital Center, Cadi Ayyad University, Marrakesh, MAR.
Mohamed ChraaNeurology, Mohammed VI University Hospital Center, Marrakesh, MAR.
Nissrine LouhabNeurology, Mohammed VI University Hospital Center, Cadi Ayyad University, Marrakesh, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon monoxide (CO) poisoning is the leading cause of death from accidental poisoning worldwide. It is associated with significant mortality and morbidity. The mere notion of exposure to risk should lead to the diagnosis of CO poisoning in an emergency situation. Neurological (coma and delayed neuropsychological sequelae) and cardiac (ischemic changes with normal coronary arteries) clinical scenarios are explained by complex mechanisms: carboxyhemoglobin formation, cytochrome oxidase inhibition, oxidative stress, as well as ischemia-reperfusion phenomenon. Delayed neurological sequelae (DNS) or delayed encephalopathy is characterized by a neurological clinical picture that arises after acute CO intoxication and after a period of apparent recovery. The onset of DNS is unpredictable. The true prevalence of DNS is difficult to determine; the estimates range from 1% to 47% of patients after CO poisoning. The exact incidence rate is also unclear. Studies using rigorous methodologies, including neuropsychological testing, report the frequency to be as high as 67%. CO poisoning causes severe neurocognitive after-effects that are rarely studied in the literature. Here, we describe the case of a patient aged 18 years old with no known comorbidities, a victim of accidental CO poisoning, who initially presented with behavioral disorders. The evolution was marked by the occurrence of memory and attention disorders a few weeks later. Neuropsychological assessment revealed a dysfunction of several processes (executive, attentional, and memory). Brain MRI revealed restrictive bilateral occipital, frontal, and temporal lesions of hypoxic origin. The patient underwent three sessions of hyperbaric oxygen therapy and received symptomatic drug treatment and neurocognitive rehabilitation, with a more or less favorable evolution of her disorders.

Indexed as

brain mricarbone monoxide poisoningdnshbot (hyperbaric oxygen therapy)neurocognitive

Identifiers

PMID40519477
PMCPMC12162377

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.