Evidence map›Paper›PMID 40519766›Full record

ArticleVisceral medicine2025

Use of Histomorphological Features for the Prediction of Grade C Fistula after Whipple Procedure: A Difficult Task.

Tim Fahlbusch, Georgios Antoniou, Philipp Höhn, Andrea Tannapfel, Waldemar Uhl, Orlin Belyaev, Johanna Munding

Abstract read
In one paragraph

Article in Visceral medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tim FahlbuschDepartment of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany.
Georgios AntoniouDepartment of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany.
Philipp HöhnDepartment of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany.
Andrea TannapfelInstitute of Pathology, Ruhr-University Bochum, Bochum, Germany.
Waldemar UhlDepartment of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany.
Orlin BelyaevDepartment of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany.
Johanna MundingInstitute of Pathology, Ruhr-University Bochum, Bochum, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The prediction of occurrence and form of a postoperative pancreatic fistula (POPF) could decrease the risk after pancreatic resections. We developed a score based on histomorphological criteria to predict POPF earlier on. In this study, we test the scoring system to differentiate between patients developing grades B and C POPF. Methods: We analysed 92 patients who underwent pancreatic head resection and developed a grade B or C POPF postoperatively. There were no exclusion criteria. Pancreatic resection margins were analysed histologically and pancreatic duct size, fibrosis, fat content, and signs of inflammation were transformed into a scoring system. Results: Patients with a grade B fistula ( Conclusion: Establishing a score to differentiate between grade B and grade C POPF is a difficult task. Pancreatic fat seems to be the most relevant histomorphological feature to be used in any scoring system, and it should be combined with other clinical features to enhance its precision and validity.

Indexed as

HistologyPancreasPostoperative pancreatic fistulaResection marginSurgery

Identifiers

PMID40519766
PMCPMC12165639

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.