ReviewFrontiers in pharmacology2025
Dachengqi decoction for the treatment of acute pancreatitis: a comprehensive analysis based on metabolites, pharmacokinetics, and metabolites efficacy mechanisms.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Plants and Plant-Derived Compounds Mediate Protection Across Diverse Pathological Conditions by Targeting the PANoptosis Pathways.Phytotherapy research : PTR · 2026Review
- Comprehensive Evaluation of Fructus Tsaoko, Seeds of Tsaoko Fructus and Ginger Made Seeds of Tsaoko Fructus Based on Drug-Like Compounds and Aroma Analysis.Food science & nutrition · 2026Article
- Efficacy of Intestinal Obstruction Catheter Combined with Modified Dachengqi Decoction in Elderly Patients with Early Postoperative Inflammatory Intestinal Obstruction: A Randomised Study.International journal of general medicine · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Dachengqi decoction (DCQD) is a traditional Chinese medicine formula consisting of three botanical drugs and one mineral drug. It has anti-inflammatory, gastrointestinal motility, and microcirculation improvement effects. A large number of studies have shown that DCQD has a significant impact on the treatment of acute pancreatitis (AP). However, owing to the multi-component and multi-target characteristics of traditional Chinese medicine, it is difficult for modern scientists to understand the role of DCQD in treating AP. Therefore, We sorted out the literature data related to DCQD published in databases such as Web of Science, PubMed, and CNKI, and summarized the main metabolites of DCQD, including anthraquinones, flavonoids, lignans and other metabolites. The pharmacokinetic characteristics of the main metabolites entering the blood circulation are preliminarily summarized. Combining chemical analysis and network analysis, some metabolites in DCQD, such as emodin, rhein, and luteolin, may play important roles in the treatment of AP, and this review also summarizes the efficacy mechanisms of these metabolites. In brief, we have summarized the treatment of AP with DCQD from the aspects of metabolites, preliminary pharmacokinetic analysis, and efficacy mechanisms, to facilitate further understanding of the material basis of DCQD.
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Registered trials
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